ExactAb™,低内毒素,已验证,无动物源,无叠氮钠,无载体,重组 级 提供 ≥95%(SDS-PAGE&SEC-HPLC) 纯度，适用于对基线干扰要求严格的色谱和分析工作流程。
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在色谱分析、有机合成和交叉偶联反应领域已被 1 篇同行评审文献引用。
Vesencumab (anti-NRP1) 是针对 neuropilin-1 (NRP-1) 的 IG1 抗体。Vesencumab (anti-NRP1) 与 NRP-1 结合并阻止 NRP-1 与 VEGFR-2 偶联。Vesencumab (anti-NRP1) 具有抗血管生成和抗肿瘤活性。Vesencumab (anti-NRP1) 可用于转移性实体瘤的研究，包括卵巢癌。
Vesencumab (anti-NRP1) is IG1 antibody against neuropilin-1 (NRP-1). Vesencumab (anti-NRP1) binds to NRP-1 and prevents the subsequent coupling of NRP-1 to VEGFR-2. Vesencumab (anti-NRP1) has anti-angiogenic and anti-neoplastic activities. Vesencumab (anti-NRP1) can be used in the research of metastatic solid tumors, including ovarian cancer.
Purity
≥95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg
Vesencumab (anti-NRP1) (Ab183435) - Flow Cytometry
Flow Cytometry analysis of MDA-MB-231 cells labelling NRP1 (red) with Vesencumab (anti-NRP1) (Ab183435). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Vesencumab (anti-NRP1) (Ab183435) - Flow Cytometry
Flow Cytometry analysis of HeLa cells labelling NRP1 (red) with Vesencumab (anti-NRP1) (Ab183435). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Vesencumab (anti-NRP1) (Ab183435) - ELISA
Immobilized Recombinant Human NRP1-His protein at 2.0 μg/mL can bind Vesencumab (anti-NRP1) (Ab183435) with the EC₅₀ of 3.345 ng/mL.
Vesencumab (anti-NRP1) (Ab183435) - SEC
The purity of Vesencumab (anti-NRP1) (Ab183435) is more than 95% verified by HPLC.
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
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| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
 ZJ24F0910909 |
分析证书 | Ab183435 |
| ZJ24F0910910 |
分析证书 | Ab183435 |
| ZJ24F0910911 |
分析证书 | Ab183435 |
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