Rosopatamab (anti-PSMA) 是一种人源化抗 PSMA 的 IgG1 单克隆抗体，可用于癌症，尤其是前列腺癌的研究。Rosopatamab (anti-PSMA) 可通过双功能螯合剂 DOTA-NHS 酯与低能 β 发射放射性同位素 lutetium-177 (177Lu) 连接，得到高效靶向恶性前列腺细胞的放射免疫缀合物。
Rosopatamab (anti-PSMA) is a humanized antiPSMA IgG1 monoclonal antibody that can be used in cancer research, especially prostate cancer. Rosopatamab (anti-PSMA) can be linked to the low-energy beta-emitting radioisotope lutetium-177 (177Lu) through the bifunctional chelator DOTA-NHS ester to obtain a radioimmunoconjugate that targets malignant prostate cells with high efficiency.
Rosopatamab (anti-PSMA) (Ab190122) - Flow Cytometry
Flow Cytometry analysis of LNCaP cells labelling PSMA (red) with Rosopatamab (anti-PSMA) (Ab190122) at 1.0 μg/mL for 1 hour at 4°C. Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Rosopatamab (anti-PSMA) (Ab190122) - Flow
pLVX-puro-SYMX05-Hu-PSMA(Q04609)-FL cells at 1×105 cell/well can bind Rosopatamab (anti-PSMA) (Ab190122), with the EC₅₀ of 226.8 ng/mL.
Rosopatamab (anti-PSMA) (Ab190122) - SEC
The purity of Rosopatamab (anti-PSMA) (Ab190122) is more than 95% verified by HPLC.
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
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| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
 ZJ24F1013082 |
分析证书 | Ab190122 |
| ZJ24F1013083 |
分析证书 | Ab190122 |
| ZJ24F1013084 |
分析证书 | Ab190122 |
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