ExactAb™,低内毒素,已验证,无动物源,无叠氮钠,无载体,重组 级 提供 ≥95%(SDS-PAGE&SEC-HPLC) 纯度，适用于对基线干扰要求严格的色谱和分析工作流程。
-80℃储存,避免反复冻融。特低温运输 。请查阅批次 COA 获取详细规格。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
Alemtuzumab (anti-CD52)是一种抗CD52的重组单克隆抗体，CD52是一种糖蛋白，在大多数淋巴细胞表面表达，在较小程度上也表达于髓细胞类型。阿仑单抗选择性靶向CD52抗原，诱导淋巴细胞深度耗竭，然后恢复具有调节表型的 T 细胞和 B 细胞。
Alemtuzumab (anti-CD52) is a recombinant monoclonal antibody to CD52, a glycoprotein expressed on the surface of most lymphoid, and to a lesser extent, myeloid cell types. Alemtuzumab selectively targets the CD52 antigen to induce profound lymphocyte depletion, followed by recovery of T and B cells with regulatory phenotypes.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg
Alemtuzumab (anti-CD52) (Ab170481) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD52 with Alemtuzumab (anti-CD52) (Ab170481) conjugated with biotin (right panel) compared with Human IgG (Ab170213) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156150).
Alemtuzumab (anti-CD52) (Ab170481) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD52 (red) with Alemtuzumab (anti-CD52) (Ab170481) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, human IgG (Ab170213) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.
Alemtuzumab (anti-CD52) (Ab170481) - SEC
The purity of Alemtuzumab (anti-CD52) (Ab170481) is more than 95% verified by HPLC.
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
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| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
 ZJ26F0636271 |
分析证书 | Ab170481 |
| ZJ26F0636270 |
分析证书 | Ab170481 |
| ZJ26F0636269 |
分析证书 | Ab170481 |
| ZJ24F0303661 |
分析证书 | Ab170481 |
| ZJ24F0303662 |
分析证书 | Ab170481 |
| ZJ24F0303663 |
分析证书 | Ab170481 |
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