计算溶液所需的质量、体积或浓度。
| 活性类型 | 活性值-log(M) | 作用机制 | 期刊 | 参考文献(PubMed IDs) |
|---|
有货
为什么选择此级别
Moligand™ 级 提供 ≥98% 纯度，适用于对基线干扰要求严格的色谱和分析工作流程。
储存与运输
室温。常规运输 。请查阅批次 COA 获取详细规格。
质量文档
SDS、COA、产品数据表及规格说明书均可下载。可通过批号查询获取批次 COA。
文献证明
在色谱分析、有机合成和交叉偶联反应领域已被 58 篇同行评审文献引用。
概述
室温下溶解丙酮，不溶于水。It has been used to study the effect of bioflavonoids on the inhibition of ATP synthase in Escherichia coli,and also used to study the effect of Chrysin on eIF4E (eukaryotic translation initiation factor 4E) expression in AGS cell (human gastric carcinoma cell) line,used to study the effect of chrysin on human ovarian cancer cells.
It has been used to study the effect of bioflavonoids on the inhibition of ATP synthase in Escherichia coli,and also used to study the effect of Chrysin on eIF4E (eukaryotic translation initiation factor 4E) expression in AGS cell (human gastric carcinoma cell) line,used to study the effect of chrysin on human ovarian cancer cells.
规格
别名
白杨素 | 5,7-二羟基黄酮 | 5,7-二羟黄酮
英文别名
5,7-Dihydroxyflavone | 5,7-dihydroxy-2-phenyl-4H-benzo[b]pyran-4-one
规格或纯度
Moligand™, ≥98%
英文名称
Chrysin
生化机理
抗氧化剂类黄酮。抗炎和抗氧化特性，还能够诱导细胞凋亡。缺氧诱导因子1α（HIF-1α）的有效抑制剂。
应用
It has been used to study the effect of bioflavonoids on the inhibition of ATP synthase in Escherichia coli,and also used to study the effect of Chrysin on eIF4E (eukaryotic translation initiation factor 4E) expression in AGS cell (human gastric carcinoma cell) line,used to study the effect of chrysin on human ovarian cancer cells.
储存条件
室温
运输条件
常规运输
备注
如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。
纯度
≥98%
名称和识别符
PubChem SID
EC号
207-549-7
分子类型
小分子
IUPAC Name
5,7-dihydroxy-2-phenylchromen-4-one
INCHI
1S/C15H10O4/c16-10-6-11(17)15-12(18)8-13(19-14(15)7-10)9-4-2-1-3-5-9/h1-8,16-17H
InChi Key
RTIXKCRFFJGDFG-UHFFFAOYSA-N
Smiles
C1=CC=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O2)O)O
Isomeric SMILES
C1=CC=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O2)O)O
分子量
254.24
Reaxy-Rn
233276
Reaxys-RN link address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=233276&ln=
技术文档
高级数据
系统学分类
分类树（Taxonomy Tree）
| 界（kingdom) | 有机化合物 |
|---|---|
| 超类（Superclass) | 苯丙素类和聚酮类 |
| 类（Class) | 黄酮类化合物 |
| 亚类（Subclass） | 黄酮类 |
| 中间层级节点（Intermediate Tree Nodes） | 暂无 |
| 直接上位类(Direct Parent) | 黄酮类 |
| 其他上位类（Alternative Parents） | 7-羟基黄酮类化合物 5-羟基黄酮类化合物 色酮 吡喃酮及其衍生物 1-羟基-4-未取代苯类化合物 1-羟基-2-未取代苯类化合物 苯及其取代衍生物 乙烯基酸 杂芳族化合物 氧环化合物 有机氧化合物 有机氧化物 碳氢化合物衍生物 |
| 分子骨架（Molecular Framework) | 芳香族杂多环化合物 |
| 取代基（Substituents） | 1-苯并吡喃 - 1-羟基-2-未取代苯环化合物 - 1-羟基-4-未取代苯环化合物 - 5-羟基黄酮 - 7-羟基黄酮 - 芳香族杂多环化合物 - 苯基化合物 - 苯并吡喃 - 苯并吡喃 - 黄酮 - 杂芳香族化合物 - 烃衍生物 - 羟基黄酮 - 单环苯基基团 - 有机氧化物 - 有机氧化合物 - 有机杂环化合物 - 有机氧化合物 - 氧杂环 - 吡喃 - 吡喃酮 - 乙烯基羧酸 |
| 描述（Description） | 该化合物属于黄酮类有机化合物。这类黄酮类化合物以2-苯基苯并吡喃-4-酮（2-苯基-1-苯并吡喃-4-酮）为骨架结构。 |
| 外部描述符（External Descriptors） | Flavones and Flavonols |
三维结构
交互式化学结构模型
关联靶点（人）
CYP1A2
Tchem
细胞色素 P450 1A2(Cytochrome P450 1A2)
(5 活性数据)
CYP1B1
Tchem
细胞色素 P450 1B1(Cytochrome P450 1B1)
(5 活性数据)
CYP2C19
Tchem
细胞色素 P450 2C19(Cytochrome P450 2C19)
(1 活性数据)
CBR1
Tchem
羰基还原酶[NADPH] 1(Carbonyl reductase [NADPH] 1)
(2 活性数据)
CA4
Tclin
碳酸酐酶4(Carbonic anhydrase 4)
(1 活性数据)
CA12
Tclin
碳酸酐酶12(Carbonic anhydrase 12)
(1 活性数据)
CA7
Tclin
碳酸酐酶7(Carbonic anhydrase 7)
(1 活性数据)
CYP19A1
Tclin
芳香化酶(Aromatase)
(3 活性数据)
CYP1A1
Tchem
细胞色素 P450 1A1(Cytochrome P450 1A1)
(3 活性数据)
XDH
Tclin
黄嘌呤脱氢酶/氧化酶(Xanthine dehydrogenase/oxidase)
(1 活性数据)
CA2
Tclin
Carbonic anhydrase II
(17698 活性数据)
ESR1
Tclin
Estrogen receptor alpha
(17718 活性数据)
NR3C1
Tclin
Glucocorticoid receptor
(14987 活性数据)
ALDH2
Tclin
Aldehyde dehydrogenase
(509 活性数据)
ALOX5
Tclin
Arachidonate 5-lipoxygenase
(6568 活性数据)
AR
Tclin
Androgen Receptor
(11781 活性数据)
VDR
Tclin
Vitamin D receptor
(26531 活性数据)
CYP19A1
Tclin
Cytochrome P450 19A1
(6099 活性数据)
TYR
Tclin
Tyrosinase
(717 活性数据)
ACHE
Tclin
Acetylcholinesterase
(18204 活性数据)
PTGS1
Tclin
Cyclooxygenase-1
(9233 活性数据)
PTGS2
Tclin
Cyclooxygenase-2
(13999 活性数据)
PPARG
Tclin
Peroxisome proliferator-activated receptor gamma
(15191 活性数据)
XDH
Tclin
Xanthine dehydrogenase
(1038 活性数据)
PTH1R
Tclin
Parathyroid hormone receptor
(47172 活性数据)
PPARA
Tclin
Peroxisome proliferator-activated receptor alpha
(9197 活性数据)
AKR1B1
Tclin
Aldose reductase
(1404 活性数据)
RXRA
Tclin
Retinoid X receptor alpha
(3637 活性数据)
LCK
Tclin
Tyrosine-protein kinase LCK
(9212 活性数据)
CYP1B1
Tchem
Cytochrome P450 1B1
(1148 活性数据)
CA1
Tclin
Carbonic anhydrase I
(13240 活性数据)
CDK6
Tclin
Cyclin-dependent kinase 6
(1724 活性数据)
NEU2
Tbio
Sialidase 2
(382 活性数据)
AHR
Tclin
Aryl hydrocarbon receptor
(1071 活性数据)
PIM1
Tchem
Serine/threonine-protein kinase PIM1
(9629 活性数据)
SYK
Tclin
Tyrosine-protein kinase SYK
(7372 活性数据)
CYP1A1
Tchem
Cytochrome P450 1A1
(1169 活性数据)
ALDH1A1
Tchem
Aldehyde dehydrogenase 1A1
(77053 活性数据)
DAPK1
Tchem
Death-associated protein kinase 1
(1664 活性数据)
NR1H4
Tclin
Bile acid receptor FXR
(6228 活性数据)
CYP2D6
Tclin
Cytochrome P450 2D6
(33882 活性数据)
FBP1
Tchem
Fructose-1,6-bisphosphatase
(1199 活性数据)
HSD17B1
Tchem
Estradiol 17-beta-dehydrogenase 1
(2224 活性数据)
FASN
Tchem
Fatty acid synthase
(3390 活性数据)
TOP2B
Tclin
DNA topoisomerase II beta
(959 活性数据)
CA12
Tclin
Carbonic anhydrase XII
(6231 活性数据)
CYP1A2
Tchem
Cytochrome P450 1A2
(26471 活性数据)
FLT3
Tclin
Tyrosine-protein kinase receptor FLT3
(13481 活性数据)
PDK1
Tchem
Pyruvate dehydrogenase kinase isoform 1
(2021 活性数据)
SELL
Tchem
Leukocyte adhesion molecule-1
(145 活性数据)
UGT1A4
Tbio
UDP-glucuronosyltransferase 1A4
(288 活性数据)
CYP2C9
Tchem
Cytochrome P450 2C9
(32119 活性数据)
CYP2C19
Tchem
Cytochrome P450 2C19
(29246 活性数据)
CA9
Tclin
Carbonic anhydrase IX
(8255 活性数据)
HSD17B2
Tchem
Estradiol 17-beta-dehydrogenase 2
(1671 活性数据)
CYP3A4
Tclin
Cytochrome P450 3A4
(53859 活性数据)
TP53
Tchem
Cellular tumor antigen p53
(48468 活性数据)
CYP2A6
Tchem
Cytochrome P450 2A6
(2861 活性数据)
CYP2B6
Tchem
Cytochrome P450 2B6
(1338 活性数据)
A-375
(9258 活性数据)
关联靶点（其它种属）
NA
Neuraminidase (1107 活性数据)
Ca7
Carbonic anhydrase VII (3 活性数据)
Glo1
Glyoxalase I (4 活性数据)
Sele
Selectin E (1 活性数据)
Abcc1
Multidrug resistance-associated protein 1 (42 活性数据)
Selp
P-selectin (7 活性数据)
Ppard
Peroxisome proliferator-activated receptor delta (358 活性数据)
Abcb1b
P-glycoprotein 1 (174 活性数据)
CA4
Carbonic anhydrase IV (1713 活性数据)
Nos2
Nitric oxide synthase, inducible (3573 活性数据)
Mapk1
MAP kinase ERK2 (650 活性数据)
Hdac6
Histone deacetylase 6 (222 活性数据)
Faah
Anandamide amidohydrolase (3907 活性数据)
pol
Human immunodeficiency virus type 1 integrase (9041 活性数据)
Pseudomonas fluorescens (1630 活性数据)
Salmonella typhimurium (15756 活性数据)
Staphylococcus aureus (210822 活性数据)
Staphylococcus epidermidis (22802 活性数据)
Klebsiella aerogenes (4963 活性数据)
Escherichia coli (133304 活性数据)
Bacillus subtilis (32866 活性数据)
Mycobacterium tuberculosis (203094 活性数据)
Trypanosoma brucei brucei (13300 活性数据)
Entamoeba histolytica (2676 活性数据)
Plasmodium falciparum (966862 活性数据)
Taenia crassiceps (97 活性数据)
Mus musculus (284745 活性数据)
Rattus norvegicus (775804 活性数据)
Human alphaherpesvirus 1 (11089 活性数据)
Human immunodeficiency virus 1 (70413 活性数据)
Hepatitis C virus (23859 活性数据)
Stenotrophomonas maltophilia (1743 活性数据)
3T3-L1 (3664 活性数据)
L1210 (27553 活性数据)
RBL-2H3 (1162 活性数据)
Vero (26788 活性数据)
BV-2 (3710 活性数据)
L929 (3802 活性数据)
H22 (575 活性数据)
LOX1.1
Seed lipoxygenase-1 (463 活性数据)
Syrian golden hamster (1610 活性数据)
fabG
3-oxoacyl-acyl-carrier protein reductase (70 活性数据)
fabI
Enoyl-acyl-carrier protein reductase (415 活性数据)
B16-F10 (4610 活性数据)
Chromobacterium violaceum (349 活性数据)
Lysinibacillus sphaericus (157 活性数据)
Plcg2
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 (5 活性数据)
PLCG1
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 (24 活性数据)
Luciferin 4-monooxygenase (66902 活性数据)
rep
Replicase polyprotein 1ab (378 活性数据)
作用机制
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
化学和物理性质
密度
1.443
熔点
285-286°C
分子量
254.240 g/mol
XLogP3
2.100
氢键供体数Hydrogen Bond Donor Count
2
氢键受体数Hydrogen Bond Acceptor Count
4
可旋转键计数Rotatable Bond Count
1
精确质量Exact Mass
254.058 Da
单同位素质量Monoisotopic Mass
254.058 Da
拓扑极表面积Topological Polar Surface Area
66.800 Ų
重原子数Heavy Atom Count
19
形式电荷Formal Charge
0
复杂度Complexity
384.000
同位素原子数Isotope Atom Count
0
定义的原子立体中心计数Defined Atom Stereocenter Count
0
未定义的原子立体中心计数Undefined Atom Stereocenter Count
0
定义的键立体中心计数Defined Bond Stereocenter Count
0
未定义的键立体中心计数Undefined Bond Stereocenter Count
0
所有立体化学键的总数The total count of all stereochemical bonds
0
共价键合单元计数Covalently-Bonded Unit Count
1
安全和危险性（GHS）
Merck Index
2256
质检证书（CoA,COO,BSE/TSE 和分析图谱)
C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:
通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！
| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
 H2202136 |
分析证书 | C110079 |
| H2202137 |
分析证书 | C110079 |
| A2217083 |
分析证书 | C110079 |
| K2116351 |
分析证书 | C110079 |
| G2102046 |
分析证书 | C110079 |
| L2425261 |
分析证书 | C110079 |
| E2423203 |
分析证书 | C110079 |
| E2423204 |
分析证书 | C110079 |
| E2423205 |
分析证书 | C110079 |
| E2423206 |
分析证书 | C110079 |
| G2502558 |
分析证书 | C110079 |
| L2517053 |
分析证书 | C110079 |
| F2305943 |
分析证书 | C110079 |
| H2202135 |
分析证书 | C110079 |
| H2202138 |
分析证书 | C110079 |
| F2305945 |
分析证书 | C110079 |
显示更多⌵
技术文档和文章
此产品的引用文献
引用文献
| 1. Lei Liu, Yingyu Sima, Jinxia Feng, Shuting Shi, Aiting Chen, Chuanqin Zhou, Quanguo He, Yimin Tan. (2023) Bismuth oxide and nitrogen-doped reduced graphene oxide co-modified glassy carbon electrode to perform sensitive electrochemical sensing and determination of chrysin in pharmaceutical capsules. MICROCHEMICAL JOURNAL, [10.1016/j.microc.2023.109544] |
| 2. Shuang Xiao, Peng Zhang, Guowen Zhang, Wenwen Li, Haowen Lin, Xing Hu. (2023) Inhibition of toll-like receptor 4 activation by apigenin and chrysin via competition for sites and conformational changes. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:37598817] [10.1016/j.ijbiomac.2023.126415] |
| 3. Xinyan Tao, Yuan Liu, Zhenhua Ding, Shuang Xie, Wenxiong Cao, Xiaohong Li. (2023) Injectable cell-targeting fiber rods to promote lipolysis and regulate inflammation for obesity treatment. Biomaterials Science, [PMID:37432672] [10.1039/D3BM00619K] |
| 4. Shaoyan Zhang, Jinfeng Ning, Qingqing Wang, Wei Wang. (2023) Fluorescence enhancement of flavonoids and its application in ingredient determination for some traditional Chinese medicines by CE-LIF. Analytical Methods, 15 (24): (2964-2970). [PMID:37309583] [10.1039/D3AY00486D] |
| 5. Zhifeng Cai, Yi Zhang, Yiming Zhang, Yongjie Bai, Jiayue Huang, Zijing Guo, Huangjing Bao, Jiayi Zhang. (2023) One-pot simple preparation of bright blue emitting copper nanoclusters for sensitive detection of chrysin via inner filter effect. JOURNAL OF LUMINESCENCE, [10.1016/j.jlumin.2023.119781] |
| 6. Ruiyi Fan, Congyi Zhu, Diyang Qiu, Genlin Mao, Bernd Mueller-Roeber, Jiwu Zeng. (2023) Integrated transcriptomic and metabolomic analyses reveal key genes controlling flavonoid biosynthesis in Citrus grandis ‘Tomentosa’ fruits. PLANT PHYSIOLOGY AND BIOCHEMISTRY, [PMID:36724705] [10.1016/j.plaphy.2023.01.050] |
| 7. Chun Xiao Li, Fu Rong Wang, Bing Zhang, Ze Yuan Deng, Hong Yan Li. (2023) Stability and antioxidant activity of phenolic compounds during in vitro digestion. JOURNAL OF FOOD SCIENCE, 88 (2): (696-716). [PMID:36617678] [10.1111/1750-3841.16440] |
| 8. Qizhi Zhang, Wenmei Yu, Zhenhua Liu, Hui Li, Yihui Liu, Xin Liu, Zhaoshun Han, Jun He, Yaofu Zeng, Yu Guo, Yunmei Liu. (2023) Design, synthesis, antitumor activity and ct-DNA binding study of photosensitive drugs based on porphyrin framework. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:36621729] [10.1016/j.ijbiomac.2023.123147] |
| 9. Mang-Mang Li, Yi-Ting Chen, Jin-Cang Ruan, Wen-Jun Wang, Ji-Guang Chen, Qing-Feng Zhang. (2022) Structure-activity relationship of dietary flavonoids on pancreatic lipase. Current Research in Food Science, [PMID:36618100] [10.1016/j.crfs.2022.100424] |
| 10. Xijuan Tu, Fengjie Yu, Qian Jin, Chunping Du, Jiaxu Chen, Ji Yang, Yuchang He, Shaokang Huang, Wenbin Chen. (2022) A Simple High-Throughput Field Sample Preparation Method Based on Matrix-Induced Sugaring-Out for the Simultaneous Determination of 5-Hydroxymethylfurfural and Phenolic Compounds in Honey. MOLECULES, 27 (23): (8373). [PMID:36500464] [10.3390/molecules27238373] |
| 11. Wenjie Yu, Fengjie Sun, Ruixin Xu, Meng Cui, Yongquan Liu, Quanyuan Xie, Limin Guo, Chenxian Kong, Xin Li, Xiali Guo, Liping Luo. (2022) Chemical composition and anti-inflammatory activities of Castanopsis honey. Food & Function, 14 (1): (250-261). [PMID:36484340] [10.1039/D2FO02233H] |
| 12. Lingli Zhao, Mengfei Zheng, Hao Cai, Juan Chen, Yan Lin, Fangbin Wang, Lu Wang, Xian Zhang, Jian Liu. (2022) The activity comparison of six dietary flavonoids identifies that luteolin inhibits 3T3-L1 adipocyte differentiation through reducing ROS generation. JOURNAL OF NUTRITIONAL BIOCHEMISTRY, [PMID:36370929] [10.1016/j.jnutbio.2022.109208] |
| 13. Jie Zhao, Lin Huang, Renjie Li, Zhuangwei Zhang, Jin Chen, Hongjin Tang. (2022) Insights from multi-spectroscopic analysis and molecular modeling to understand the structure–affinity relationship and the interaction mechanism of flavonoids with gliadin. Food & Function, 13 (9): (5061-5074). [PMID:35404372] [10.1039/D1FO03816H] |
| 14. Zuoxing Wu, Chen Li, Yu Chen, Qian Liu, Na Li, Xuemei He, Weibin Li, Rong Shen, Li Li, Chenming Wei, Siyuan Shao, Fangsheng Fu, Jiaxin Ding, Xiaochen Sun, Dairong Wang, Guixin Yuan, Yiji Su, Jinmin Zhao, Jiake Xu, Ren Xu, Xin Xu, Feng Xu. (2022) Chrysin Protects Against Titanium Particle-Induced Osteolysis by Attenuating Osteoclast Formation and Function by Inhibiting NF-κB and MAPK Signaling. Frontiers in Pharmacology, [PMID:35401243] [10.3389/fphar.2022.793087] |
| 15. Jie Zhao, Lin Huang, Renjie Li, Zhuangwei Zhang, Jin Chen, Hongjin Tang. (2022) Multispectroscopic and computational evaluation of the binding of flavonoids with bovine serum albumin in the presence of Cu2+. FOOD CHEMISTRY, [PMID:35279499] [10.1016/j.foodchem.2022.132656] |
| 16. Hongjin Tang, Lin Huang, Dongsheng Zhao, Chunyong Sun, Ping Song. (2020) Interaction mechanism of flavonoids on bovine serum albumin: Insights from molecular property-binding affinity relationship. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:32480277] [10.1016/j.saa.2020.118519] |
| 17. Jie Zhao, Lin Huang, Chunyong Sun, Dongsheng Zhao, Hongjin Tang. (2020) Studies on the structure-activity relationship and interaction mechanism of flavonoids and xanthine oxidase through enzyme kinetics, spectroscopy methods and molecular simulations. FOOD CHEMISTRY, [PMID:32330646] [10.1016/j.foodchem.2020.126807] |
| 18. Ding Liu, Qizhi Zhang, Lang Zhang, Wenmei Yu, Huizhi Long, Jun He, Yunmei Liu. (2020) Novel photosensitizing properties of porphyrin–chrysin derivatives with antitumor activity in vitro. JOURNAL OF CHEMICAL RESEARCH, [10.1177/1747519820907248] |
| 19. Su Liqiang, Li Jijiao, Han Shuang. (2019) Controllable Preparation and Application of Quercetin Molecularly Imprinted Polymer. RUSSIAN JOURNAL OF APPLIED CHEMISTRY, 92 (7): (972-981). [10.1134/S1070427219070140] |
| 20. Chengyun He, Xiaoling Liu, Zhaojing Jiang, Sheng Geng, Hanjun Ma, Benguo Liu. (2019) Interaction Mechanism of Flavonoids and α-Glucosidase: Experimental and Molecular Modelling Studies. Foods, 8 (9): (355). [PMID:31438605] [10.3390/foods8090355] |
| 21. Yao Yu, Cheng Xu, Le Zhen, Shan Yang, Jianping Zhou, Jing Yao. (2019) Bio-inspired drug-dominated supramolecular nanocomplex based on low molecular weight heparin for progressive tumor therapy. CARBOHYDRATE POLYMERS, [PMID:31196548] [10.1016/j.carbpol.2019.05.051] |
| 22. Qian Liu, Hai-Long Wu, Zhi Liu, Rong Xiao, Tong Wang, Yong Hu, Yu-Jie Ding, Ru-Qin Yu. (2018) Chemometrics-assisted HPLC-DAD as a rapid and interference-free strategy for simultaneous determination of 17 polyphenols in raw propolis. Analytical Methods, 10 (46): (5577-5588). [10.1039/C8AY01986J] |
| 23. Shishi Li, Jinjin Xu, Zhihong Yao, Liufang Hu, Zifei Qin, Hao Gao, Kristopher W. Krausz, Frank J. Gonzalez, Xinsheng Yao. (2018) The roles of breast cancer resistance protein (BCRP/ABCG2) and multidrug resistance-associated proteins (MRPs/ABCCs) in the excretion of cycloicaritin-3-O-glucoronide in UGT1A1-overexpressing HeLa cells. CHEMICO-BIOLOGICAL INTERACTIONS, [PMID:30237061] [10.1016/j.cbi.2018.09.001] |
| 24. Yang Mei, Xiong Jun, Zou Qiang, Wang Dan-Dan, Huang Cong-Xin. (2018) Chrysin attenuates interstitial fibrosis and improves cardiac function in a rat model of acute myocardial infarction. JOURNAL OF MOLECULAR HISTOLOGY, 49 (6): (555-565). [PMID:30225683] [10.1007/s10735-018-9793-0] |
| 25. Hui Wang, Wenxi Zhang, Yatao Cheng, Xinyu Zhang, Nannan Xue, Gaorong Wu, Meng Chen, Kang Fang, Wenbo Guo, Fei Zhou, Herong Cui, Tao Ma, Penglong Wang, Haimin Lei. (2018) Design, Synthesis and Biological Evaluation of Ligustrazine-Flavonoid Derivatives as Potential Anti-Tumor Agents. MOLECULES, 23 (9): (2187). [PMID:30200208] [10.3390/molecules23092187] |
| 26. Qing-Hui Wen, Lang-Hong Wang, Xin-An Zeng, De-Bao Niu, Man-Sheng Wang. (2018) Hydroxyl-related differences for three dietary flavonoids as inhibitors of human purine nucleoside phosphorylase. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:29894785] [10.1016/j.ijbiomac.2018.06.045] |
| 27. Han Peng, Zeyuan Deng, Xuan Chen, Yong Sun, Bing Zhang, Hongyan Li. (2018) Major chemical constituents and antioxidant activities of different extracts from the peduncles of Hovenia acerba Lindl. INTERNATIONAL JOURNAL OF FOOD PROPERTIES, [10.1080/10942912.2018.1497059] |
| 28. Geyuan Li, Kai Zhang, Meriem Fizir, Muchuan Niu, Cheng Sun, Shuangling Xi, Xuanhong Hui, Jianrong Shi, Hua He. (2017) Rational design, preparation and adsorption study of a magnetic molecularly imprinted polymer using a dummy template and a bifunctional monomer. NEW JOURNAL OF CHEMISTRY, 41 (15): (7092-7101). [10.1039/C7NJ00689F] |
| 29. Zhengkun Xie, Gaiping Li, Yamin Fu, Mengjiao Sun, Baoxian Ye. (2017) Sensitive, simultaneous determination of chrysin and baicalein based on Ta2O5-chitosan composite modified carbon paste electrode. TALANTA, [PMID:28153298] [10.1016/j.talanta.2017.01.021] |
| 30. Dong Dong, Enxi Quan, Xue Yuan, Qian Xie, Zhijie Li, Baojian Wu. (2016) Sodium Oleate-Based Nanoemulsion Enhances Oral Absorption of Chrysin through Inhibition of UGT-Mediated Metabolism. MOLECULAR PHARMACEUTICS, [PMID:27983856] [10.1021/acs.molpharmaceut.6b00851] |
| 31. Shuzhen Yang, Jie Zhou, Dongmei Li, Chunyu Shang, Litao Peng, Siyi Pan. (2016) The structure-antifungal activity relationship of 5,7-dihydroxyflavonoids against Penicillium italicum. FOOD CHEMISTRY, [PMID:28159264] [10.1016/j.foodchem.2016.12.001] |
| 32. Zhengkun Xie, Yongmei Wu, Sheng Kai, Gaiping Li, Baoxian Ye. (2016) A Newly Competitive Electrochemical Sensor for Sensitive Determination of Chrysin Based on Electrochemically Activated Ta2O5 Particles Modified Carbon Paste Electrode. ELECTROANALYSIS, 29 (3): (835-842). [10.1002/elan.201600442] |
| 33. Yue Liu, Jia Hu, Yan Li, Xiao-Shuang Li, Zhong-Liang Wang. (2016) Metal-organic framework MIL-101 as sorbent based on double-pumps controlled on-line solid-phase extraction coupled with high-performance liquid chromatography for the determination of flavonoids in environmental water samples. ELECTROPHORESIS, 37 (19): (2478-2486). [PMID:27434722] [10.1002/elps.201600118] |
| 34. Qin Tang, Fangling Ji, Jianli Guo, Jingyun Wang, Yachen Li, Yongming Bao. (2016) Directional modification of chrysin for exerting apoptosis and enhancing significantly anti-cancer effects of 10-hydroxy camptothecin. BIOMEDICINE & PHARMACOTHERAPY, [PMID:27470413] [10.1016/j.biopha.2016.06.008] |
| 35. Hongyan He, Ying Huang, Qi Zhang, Jian-Rong Wang, Xuefeng Mei. (2016) Zwitterionic Cocrystals of Flavonoids and Proline: Solid-State Characterization, Pharmaceutical Properties, and Pharmacokinetic Performance. CRYSTAL GROWTH & DESIGN, [10.1021/acs.cgd.6b00142] |
| 36. Yang Hongli, Huang Zhongping, Chen Yin, Zhang Changjun, Ye Mengdie, Wang Lili. (2015) Evaluation of the contributions of polyphenols in Chinese propolis by on-line HPLC–ABTS method. EUROPEAN FOOD RESEARCH AND TECHNOLOGY, 242 (4): (537-546). [10.1007/s00217-015-2564-1] |
| 37. Hua Sun, Xiaotong Zhou, Baojian Wu. (2015) Accurate identification of UDP-glucuronosyltransferase 1A1 (UGT1A1) inhibitors using UGT1A1-overexpressing HeLa cells. XENOBIOTICA, [PMID:26068529] [10.3109/00498254.2015.1033502] |
| 38. Yan-Mei Sun, Hai-Long Wu, Jian-Yao Wang, Zhi Liu, Min Zhai, Ru-Qin Yu. (2014) Simultaneous determination of eight flavonoids in propolis using chemometrics-assisted high performance liquid chromatography-diode array detection. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, [PMID:24907544] [10.1016/j.jchromb.2014.05.027] |
| 39. Junyan Wang, Minmin Huang, Haihong Hu, Lushan Yu, Su Zeng. (2014) Pregnane X receptor-mediated transcriptional activation of UDP-glucuronosyltransferase 1A1 by natural constituents from foods and herbs. FOOD CHEMISTRY, [PMID:24996308] [10.1016/j.foodchem.2014.05.004] |
| 40. Ting Wu, Xixi Zang, Mengying He, Siyi Pan, Xiaoyun Xu. (2013) Structure–Activity Relationship of Flavonoids on Their Anti-Escherichia coli Activity and Inhibition of DNA Gyrase. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, [PMID:23926942] [10.1021/jf402222v] |
| 41. Rui Yang, Kan Zhang. (2025) Design and Synthesis of Flavonoid-Based Mono-, Bis-, and Tri-Benzoxazines: Toward Elucidating Roles of Oxazine Ring Number and Hydrogen Bonding on Their Polymerization Mechanisms and Thermal Properties. MACROMOLECULES, [10.1021/acs.macromol.4c02616] |
| 42. Li-Feng Li, Meng-Di Wang, Chen-Yang Zhang, Meng-Yao Jin, Hua-Lei Chen, Huan Luo, Tian-Yu Hou, Zhi-Jun Zhang, He Li. (2025) Influence of hydroxyl substitution on the inhibition of flavonoids in advanced glycation end-products formation in glucose-lysine-arginine Maillard reaction models. FOOD RESEARCH INTERNATIONAL, [PMID:40086959] [10.1016/j.foodres.2025.116068] |
| 43. Yuqing Zhang, Yaping Li, Yuhan Zhai, Xing Zhao, Mingxing Lv, Shaoxuan Yu, Haifang Xiao, Yuanda Song. (2024) Inhibitory mechanism of chrysin and diosmetin to α-glucosidase: insights from kinetics, multispectroscopy and molecular docking investigations. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, [PMID:38289727] [10.1080/07391102.2024.2310207] |
| 44. Detao Li, Zichen Ning, Zhuoshan Gong, Limin Zhou, Li Xu, Feiqiang He, Hamza Shehzad, Heng Jerry, Shichao Du, Jinbo Ouyang. (2025) Insights into salts/cocrystals formation of polyhydroxy natural products as well as their separation behavior via cocrystallization. SEPARATION AND PURIFICATION TECHNOLOGY, [10.1016/j.seppur.2025.131453] |
| 45. Yijia Kang, Zhilan Qian, Haishuang Yu, Jian Lu, Qing Zhao, Xue Qiao, Min Ye, Xiangshan Zhou, Menghao Cai. (2024) Programmable Biosynthesis of Plant-Derived 4′-Deoxyflavone Glycosides by an Unconventional Yeast Consortium. Small Methods, [PMID:38348919] [10.1002/smtd.202301371] |
| 46. Xingzhu Tang, Lingling Wang, Yajie Zhang, Chaofan Sun. (2024) Relationship between antioxidant activity and ESIPT process based on flavonoid derivatives: A comprehensive analysis. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:39531972] [10.1016/j.saa.2024.125370] |
| 47. Xu Ji, Liangxi Li, Kaiyue Zhang, Xinyi Yuan, Qian Li, Ge Bai. (2024) Screening and analysis of the targeted compounds in Choerospondias axillaris extract by receptor chromatographic column with immobilized angiotensin II type 1 receptor. BIOMEDICAL CHROMATOGRAPHY, 38 (8): (e5931). [PMID:38881185] [10.1002/bmc.5931] |
| 48. Jiang Youwei, Sima Yingyu, Alomar Taghrid S., AlMasoud Najla, El-Bahy Zeinhom M., Feng Jinxia, Wan Kun, Toktarbay Zhexenbek, He Quanguo, Ding Jianhua, Wang Jingfeng, Wang Wu. (2024) Ultrasensitive and simultaneous detection for bioactive compounds of baicalein and chrysin in traditional Chinese medicine via Bi2MoO6-MWCNTs based sensing platform. Advanced Composites and Hybrid Materials, 7 (6): (1-16). [10.1007/s42114-024-01003-4] |
| 49. Ding Liu, Yan-peng Li, Hong-xiu Shen, Yang Li, Jun He, Qi-zhi Zhang, Yun-mei Liu. (2018) Synthesis and anti-tumor activities of novel 7-O-amino acids chrysin derivatives. Chinese Herbal Medicines, [10.1016/j.chmed.2018.07.002] |
| 50. Jiayi Zhang, Jingzhi Wang, Junfeng Wang, Weifeng Ni, Shichao Liu, Daqing Zhao, Zhengqi Dong, Shiting Yu, Siming Wang, Weinan Wang, Meichen Liu. (2025) Integrated multi-omics and machine learning reveal the intrinsic relationship between color and flavor variations in processed ginseng products through major pigment dynamics and non-enzymatic pathways. LWT-FOOD SCIENCE AND TECHNOLOGY, [10.1016/j.lwt.2025.118161] |
| 51. Yingao Zhai, Kunshan Wang, Zenghui Yu, Suzhen Zhou, Jinbo Fan. (2025) Pancreatic lipase inhibitors: Virtual screening and mechanistic analysis. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:40253015] [10.1016/j.ijbiomac.2025.143128] |
| 52. Haolin Zhang, Jingjing Zhang, Hui Cao, Petra Högger, Randolph Arroo, Mohamed A. Farag, Avi Shpigelman, Jianbo Xiao, Chunlin Li. (2025) Amination of Flavonoids Possessing a Pyrogallol Group in Cell Culture Medium at 37°C. Food Frontiers, 6 (2): (1058-1078). [10.1002/fft2.70002] |
| 53. Ziang Zhao, Xinyi Fang, Yanbing Gao, Qiaomei Sun. (2025) Hydroxyl substitution patterns affect flavonoid–HSA binding: Mechanistic insights from multispectral spectroscopy and molecular simulations. FOOD CHEMISTRY, [PMID:41175619] [10.1016/j.foodchem.2025.146803] |
| 54. Yongmei Chen, Qingwen Wei, Jing Wang, Chuanyao Huang, Zhenghao Wang, Yuchun Liu. (2025) Studies on the Flavonoid Composition of Pleioblastus amarus Leaves and Shoots Based on Targeted Metabolomics. Metabolites, 15 (11): (709). [PMID:41295295] [10.3390/metabo15110709] |
| 55. Dahe Qiao, Chun Yang, Xiaozeng Mi, Sihui Liang, Yan Guo, Juan Chen, Zhengwu Chen. (2026) Comprehensive evaluation of tea processing quality characteristics in ‘Qiancha 1′ tea plant cultivar: chemical profiling across tea types from multi-grade raw materials. Applied Food Research, 6 (1): (101723). [10.1016/j.afres.2026.101723] |
| 56. Changhai Sun, Mengxin Xiao, Biyue Cui, Shiyuan Sun, Shushuang Shen, Shuting Zhang, Xinran Zhang, Liting Mu. (2026) Study on the Correlation Between Anthoxanthins Compounds' Reverse-Phase Chromatographic Behavior and Their Solubility. JOURNAL OF MOLECULAR STRUCTURE, [10.1016/j.molstruc.2026.145944] |
| 57. Luyan Liu, Kaiyue Sun, Xin Xie, Yanghui Chen, Jiahui Wang, Yaxin He, Junjie Yu, Meng Huang, Yan Lin, Juan Chen, Jian Liu, Xian Zhang. (2026) Dietary myricetin inhibits AGEs formation during thermal processing in different pattern diets and alleviates AGEs-induced intestinal epithelial damage in Caco-2 cells. FOOD CHEMISTRY, [10.1016/j.foodchem.2026.148959] |
| 58. Jingjing Zhang, Hui Cao, Bing Li, Fuying Wang, Qin Duan, Yaru Li, Jinjin Pei, Hui Wang, Juan Carlos Mejuto, Jesús Simal-Gándara, Haolin Zhang. (2026) Bidirectional regulation of heterocyclic amines by flavonoids: insights from flavonoid amination using dihydromyricetin and baicalein. FOOD CHEMISTRY, [10.1016/j.foodchem.2026.150818] |
溶液计算器
常见问题
本产品的纯度是多少？
本产品的化学纯度（含量）为 ≥98%。批次的具体数值以分析证书（COA）为准。
「Moligand?」是什么？
「Moligand?」是阿拉丁科学的高端产品线之一，专为多个工作流程中的高纯度应用而设计。与同类工作流程中的标准级别相比，「Moligand?」产品通常具有更严格的规格、更严谨的 QC 以及更强的批间一致性。
本产品应如何储存？
请于室温条件下保存。
本产品如何运输？
本产品按常温标准条件运输，无需温控包装。
本产品的 CAS 号、分子式和分子量是多少？
本产品的 CAS 号为 480-40-0，分子式为 C15H10O4，分子量为 254.24 g/mol。InChIKey RTIXKCRFFJGDFG-UHFFFAOYSA-N。
如何获取批次专用COA？
每个订单都会随附分析证书（COA），您也可以从账户订单历史中下载。如需订购前的COA，请联系您的客户代表，或使用PDP上的"申请COA"按钮——我们将提供代表性批次的COA。
产品仅提供给经过验证的企业、机构和合格的专业人员用于研发。不适用于人类、动物、诊断或治疗。
Copyright © 2023至今 上海阿拉丁生化科技股份有限公司 保留所有权利。
危险品化学品经营许可证（带存储）