产品介绍
KGF角质细胞生长因子（Keratinocyte growth factor，KGF）是Rubin等（1989）从胚胎肺成纤维细胞培养上清中发现的一种细胞因子，为FGF 家族成员，即FGF-7。KGF由间质细胞分泌，受体分布于上皮细胞，是一种有效的上皮细胞特异性生长因子，其有丝分裂活性主要表现在角质形成细胞，可特异性地促进上皮细胞增殖、迁移及分化，与器官发育、创面修复、肿瘤发生及免疫重建等多方面关系密切。
OsrhKGF是运用基因重组技术，由水稻胚乳细胞表达并通过蛋白提纯工艺而成。
规格参数
来源 水稻种子
外观 白色冻干粉
活性 ≥1.0×105IU/mg
pH值 6.5-7.5
分子量 19.0 kD
内毒素 ≦0.1EU/ug
CAS No 148348-15-6
注意事项
复溶：建议用无菌水重溶OsrhKGF冻干粉至100-200 ug/ml，可用其他溶剂进行进一步稀释。溶解后的OsrhKGF 4℃可保存2-7天，尽快用完。若短期不用，请置于-20℃保存。
开启后，请尽快使用，避免污染。
使用限制
仅适于科研、实验室和生产使用，不能直接使用于人体
Product Introduction
KGF keratinocyte growth factor (KGF), a cytokine identified by Rubin et al (1989) from the culture supernatant of embryonic lung fibroblasts, is an FGF family member, namely FGF-7.KGF is secreted by stromal cells and its receptor is distributed in epithelial cells, where it is a potent epithelial cell specific growth factor, and its mitogenic activity is mainly expressed in keratinocytes, which can specifically promote epithelial cell proliferation, migration and differentiation, and is closely related to many aspects, such as organ development, wound repair, tumorigenesis and immune reconstitution.
Osrhkgf was created using genetic recombination, expressed from rice endosperm cells and through a protein purification process.
Specification parameters
Source Oryza sativa
Appearance white lyophilized powder
Activity ≥1.0×105IU/mg
pH 6.5-7.5
Molecular weight 19.0 kD
Endotoxin ≦0.1EU/ug
CAS No 148348-15-6
Matters needing attention
Reconstitution: it is recommended to lyophilize the powder of osrhkgf to 100-200 UG/ml with sterile water to make further dilutions with other solvents.The dissolved osrhkgf could be stored for 2-7 days at 4 ◦ C and used up as soon as possible.To not use for short periods, store at - 20 ℃.
Use as soon as possible after opening to avoid contamination.
Limitations of use
It is suitable for research, laboratory and production use only and cannot be used directly in humans
A2212370
危险品化学品经营许可证（带存储）