级别和纯度: 无动物源?无动物源（Animal Free）—— 不含动物源成分生产，降低污染风险。适用于避免动物源材料的生物制造和培养。无载体?无载体（Carrier Free）—— 不含添加的载体蛋白/稳定剂。当载体（如 BSA）会干扰偶联或敏感检测时使用。生物活性?生物活性级（Bioactive）—— 经验证在功能检测中保持生物活性。当分子须具有功能活性而不仅是纯度时使用。ActiBioPure™?ActiBioPure™ —— 阿拉丁面向生物活性和重组产品的优质系列。当同时需要高纯度和保持生物活性时使用。His标签?组氨酸(His) 标签级 —— 带有 His 标签的重组蛋白，供亲和纯化/检测。用于纯化、固定或检测带标签蛋白。Fc标签?Fc 标签级 —— 带有 Fc 标签的重组蛋白，供亲和纯化/检测。用于纯化、固定或检测带标签蛋白。Fc 标签有助于二聚化和 protein A/G 捕获。≥90%(SDS-PAGE)
Accession #
P36896
蛋白标签
C-His & hFc
表达系统
HEK293
内毒素水平
<0.1 EU/μg
生物活性
Measured by its binding ability in a functional ELISA. Immobilized rhActivin RIB/Fc Chimera at 2 µg/mL (100 µL/well) can bind rhCripto with a linear range of 0.8-100 ng/mL.
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Phosphorylates TDP2.
Post-translational:
Autophosphorylated.
生物活性
Measured by its binding ability in a functional ELISA. Immobilized rhActivin RIB/Fc Chimera at 2 µg/mL (100 µL/well) can bind rhCripto with a linear range of 0.8-100 ng/mL.
Recombinant Human Activin RIB/ALK-4 Protein (rp142495) - SDS-PAGE
2 μg/lane of Recombinant Human Activin RIB/ALK-4 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 46 kDa under reducing conditions and 95 & 190 kDa under non-reducing conditions.
Recombinant Human Activin RIB/ALK-4 Protein forms a disulfide-linked homodimer through its Fc domain.
ZJ25F1029145
危险品化学品经营许可证（带存储）