Measured by its ability to inhibit Activin A-induced hemoglobin expression in K562 human chronic myelogenous leukemia cells. Approximately 0.01-0.05 μg/mL of Recombinant Human (rh) Activin RIIA Fc Chimera will inhibit 50% of the biological response due to 3 ng/mL of rhActivin A.
Purity ≥95% (SDS-PAGE) Endotoxin level ＜0.1 EU/μg Function On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.
规格
产品名称
Recombinant Human Activin RIIA Protein
别名
激活素A受体ⅡA(ACVR2A)重组蛋白 | 重组人类激活素 RIIA 蛋白
英文别名
Activin receptor type IIA | ACTRIIA | ACTR-IIA | EC 2.7.11.30 | Activin A receptor type IIA | Activin receptor type 2A | Activin receptor type IIA | Activin receptor type-2A | ACTR 2 | ACTR IIA | ACTR-IIA | ACTR2 | ACTRII | ACTRIIA | Acvr 2A | Acvr 2 | Ac
Measured by its ability to inhibit Activin A-induced hemoglobin expression in K562 human chronic myelogenous leukemia cells. Approximately 0.01-0.05 μg/mL of Recombinant Human (rh) Activin RIIA Fc Chimera will inhibit 50% of the biological response due to 3 ng/mL of rhActivin A.
30.0 - 35.0 kDa, under reducing conditions; 30.0 - 35.0 kDa, under non-reducing conditions.
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
冻干(Lyophilized)
储存缓冲液
Lyophilized from 10mM PBS, 5% Trehalose, 5% Mannitol, pH 7.4
复溶
Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
在 -20~-80℃ 下可保存 1 年以上。收货后建议分装。避免冷冻/解冻循环。
图片
Recombinant Human Activin RIIA Protein (rp142510) - SDS-PAGE 3 μg/lane of Recombinant Human Activin RIIA Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 30.0 - 35.0 kDa.
ZJ24F0606775
危险品化学品经营许可证（带存储）