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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
CXCL5是一种小细胞因子，也被称为上皮中性粒细胞激活肽78(ena - 78)。这种蛋白质是在炎症细胞因子刺激细胞后产生的白细胞介素-1或肿瘤坏死因子。体外实验中，ENA-78(8-78)和ENA-78(9-78)使得中性粒细胞的趋化活性提高三倍。它们是由从外周血单核细胞分泌后的蛋白质水解产生的。重组人CXCL5 (5-78 a.a.)含有74个氨基酸，它是一个单一的非糖基化多肽链。人CXCL5有57%的氨基酸序列与小鼠和大鼠CXCL5相同。重组人ENA-78/CXCL5是一个8.1kDa大小的蛋白，含有74个氨基酸残基。
Purity
>97% SDS-PAGE or HPLC analyses. Endotoxin level is Less than 0.1EU/µg .
Function
Involved in neutrophil activation. In vitro, ENA-78(8-78) and ENA-78(9-78) show a threefold higher chemotactic activity for neutrophil granulocytes.
Post-translational
N-terminal processed forms ENA-78(8-78) and ENA-78(9-78) are produced by proteolytic cleavage after secretion from peripheral blood monocytes.
CXCL5 is a small cytokine also known as epithelial-derived neutrophil-activating peptide 78 (ENA-78). The protein is produced following stimulation of cells with the inflammatory cytokine interleukin-1 or tumor necrosis factor-alpha. In vitro, ENA-78 (8-78) and ENA-78 (9-78) show a threefold higher chemotactic activity for neutrophil granulocytes. They are produced by proteolytic cleavage after secretion from peripheral blood monocytes. Recombinant human CXCL5 (5-78 a.a.) contains 74 amino acids and it is a single non-glycosylated polypeptide chain. Human CXCL5 shares 57% amino acid sequence identity with mouse and rat CXCL5. Recombinant Human ENA-78/CXCL5 is an 8.1kDa protein containing 74 amino acid residues.
Recombinant Human CXCL5 Protein ( rp144864) - Protein Bioactivity
Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood neutrophils is in a concentration of 10.0-100.0 ng/mL.
Recombinant Human CXCL5 Protein ( rp144864) - SDS-PAGE
2.5 μg/lane of Recombinant Human CXCL5 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 9.4 kDa under reducing conditions and 12.0 kDa under non-reducing conditions.
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| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
 ZJ23F0901074 |
分析证书 | rp144864 |
| ZJ23F0901072 |
分析证书 | rp144864 |
| ZJ23F0901073 |
分析证书 | rp144864 |
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