计算溶液所需的质量、体积或浓度。
EnzymoPure™ 级 ,适用于对基线干扰要求严格的色谱和分析工作流程。
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在色谱分析、有机合成和交叉偶联反应领域已被 17 篇同行评审文献引用。
Uricase from Candida yeast has a molecular weight of ~120,000 daltons and an optimum pH of 8.5. The enzyme is stable at pH 8.5-9.5 and at temperatures below 35°C. The pI is 5.6. It is inhibited by various purine analogs of urate, and by copper chelating agents. The enzyme is highly specific for uric acid. Mice deficient in uricase develop uric acid nephropathy and diabetes insipidus which can be mitigated with recombinant uricase treatment.Oxidizes uric acid
Uricase from Candida yeast has a molecular weight of ~120,000 daltons and an optimum pH of 8.5. The enzyme is stable at pH 8.5-9.5 and at temperatures below 35°C. The pI is 5.6. It is inhibited by various purine analogs of urate, and by copper chelating agents. The enzyme is highly specific for uric acid. Mice deficient in uricase develop uric acid nephropathy and diabetes insipidus which can be mitigated with recombinant uricase treatment.
Oxidizes uric acid
| 1. Zheng Xinyu, Yang Yang, Gao Feng, Li Huihui, Yang Weikang, Guo Dong-Yu, Chen Shengming, Pan Qinhe. (2022) Enzyme-free fluorescence determination of uric acid by combining CdTe quantum dots with metal–organic framework for signal amplification. MICROCHIMICA ACTA, 189 (11): (1-9). [PMID:36318325] [10.1007/s00604-022-05535-8] |
| 2. Fuad Abduro Bushira, Shimeles Addisu Kitte, Yong Wang, Haijuan Li, Ping Wang, Yongdong Jin. (2021) Plasmon-Boosted Cu-Doped TiO2 Oxygen Vacancy-Rich Luminol Electrochemiluminescence for Highly Sensitive Detection of Alkaline Phosphatase. ANALYTICAL CHEMISTRY, [PMID:34743510] [10.1021/acs.analchem.1c03842] |
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| 10. Chenlong He, Huawei Liu, Ming Yin, Jing Chen, Wensi Huang, Han Zhou, Shengming Wu, Yilong Wang. (2025) UOx@HMnO2 Biozyme-Nanozyme Driven Electrochemical Platform for Specific Uric Acid Bioassays. ANALYST, [PMID:40035522] [10.1039/D4AN01512F] |
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| 12. Fangbing Wang, Jing Ren, Qiwen Peng, Hongyi Sun, Qiankun Zeng, Yongheng Zhang, Guoyue Shi, Min Zhang. (2024) Janus Separation-Sensing Membrane Hosted with Enzyme@MOF Nanoreactor for Real-Time Blood Sensing. ANALYTICAL CHEMISTRY, [PMID:39264829] [10.1021/acs.analchem.4c03285] |
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| 17. Sui Zhou, Wen-Qian Zhang, Yong Li, Rong-Fen Gao, Jia-Yi Ma, Kai Cheng, Jin-Xuan Fan, Jie Yang, Ling-Li Dong, Bo Liu. (2026) Multimetal-Doped Nanoenzymes Reprogram Macrophages for Immunotherapy of Gouty Arthritis. Advanced Healthcare Materials, [PMID:42396921] [10.1002/adhm.71410] |