基本描述

别名	D-脆核糖,异性树胶糖
英文别名	AC7811 \| D-(-)-Ribose, >=99.0% (sum of enantiomers, HPLC) \| BCP9000577 \| HY-W018772 \| AKOS016842327 \| SCHEMBL22679 \| C5H10O5 \| DTXSID101019160 \| SUCRALFATE [ORANGE BOOK] \| HY-109025A \| PYMYPHUHKUWMLA-LMVFSUKVSA-N \| Ribose, D- \| MFCD06799032 \| A828251 \| d(
规格或纯度	≥99%(HPLC)
英文名称	D-(-)-Ribose
生化机理	通过核糖激酶被磷酸化成D-核糖5-磷酸的戊糖单糖。[α] 20 / D -19.7°，c = 4 in H 2 O
储存温度	2-8°C储存,充氩
运输条件	冰袋运输
产品介绍	具有清凉口感的甜味，在水中的溶解度很大。 D-核糖是生物体内遗传物质——核酸的重要组成物质，在核苷类物质、蛋白质、脂肪代谢中处于枢纽位置，具有重要的生理功能及广阔的应用前景。 D-核糖作为生物体内存在于所有细胞中的天然成份，与腺苷酸的形成和ATP的再生有密切关系，是生命代谢最基本的能量来源之一。在心脏和骨络肌代谢中起关键作用，能够促进局部缺血组织、局部缺氧组织的恢复。 D-核糖是许多核酸类的重要中间体，可用于三氮唑核苷、腺苷、胸苷、胞苷、氟腺嘧啶核苷、2-甲基腺苷、威他毒素、吡唑毒素、腺苷旦氨酸等生产。

AI解读

名称和识别符

EC号	200-059-4
IUPAC Name	(2R,3R,4R)-2,3,4,5-tetrahydroxypentanal
INCHI	InChI=1S/C5H10O5/c6-1-3(8)5(10)4(9)2-7/h1,3-5,7-10H,2H2/t3-,4+,5-/m0/s1
InChi Key	PYMYPHUHKUWMLA-LMVFSUKVSA-N
Canonical SMILES	C(C(C(C(C=O)O)O)O)O
Isomeric SMILES	C([C@H]([C@H]([C@H](C=O)O)O)O)O
WGK Germany	3
RTECS	VJ2275000
PubChem CID	5311110
分子量	150.13
Beilstein号	1723081
Reaxy-Rn	1904878

化学和物理性质

溶解性	Soluble in water. Insoluble in ether.
密度	1.681
敏感性	易吸潮
比旋光度	-21 ° (C=1, H2O)
熔点	88-92°C
分子量	150.130 g/mol
XLogP3	-2.300
氢键供体数Hydrogen Bond Donor Count	4
氢键受体数Hydrogen Bond Acceptor Count	5
可旋转键计数Rotatable Bond Count	4
精确质量Exact Mass	150.053 Da
单同位素质量Monoisotopic Mass	150.053 Da
拓扑极表面积Topological Polar Surface Area	98.000 Å²
重原子数Heavy Atom Count	10
形式电荷Formal Charge	0
复杂度Complexity	104.000
同位素原子数Isotope Atom Count	0
定义的原子立体中心计数Defined Atom Stereocenter Count	3
未定义的原子立体中心计数Undefined Atom Stereocenter Count	0
定义的键立体中心计数Defined Bond Stereocenter Count	0
未定义的键立体中心计数Undefined Bond Stereocenter Count	0
所有立体化学键的总数The total count of all stereochemical bonds	0
共价键合单元计数Covalently-Bonded Unit Count	1

安全和危险性（GHS）

WGK Germany	3
RTECS	VJ2275000
Reaxy-Rn	1904878
Merck Index	8204
个人防护装备	Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

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3. Jing-Jing Liu, Zhan-Yi Wang, Bin-Bin Jiang, Shu-Qin Gao, Ying-Wu Lin. (2023) Protective effect of thymoquinone on glycation of human myoglobin induced by d-ribose. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 253 (7): (127016). [PMID:37741485] [10.1016/j.ijbiomac.2023.127016]
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参考文献

1. Min Yang, Haokun Mei, Yu Jiang, Feifang Zhang, Ziteng Yu, Bingcheng Yang. (2023) Simultaneous chromatographic separation of the anomers of saccharides on a polymer sulfobetaine zwitterionic stationary phase. JOURNAL OF SEPARATION SCIENCE, 47 (1): (2300905). [PMID:38143272] [10.1002/jssc.202300905]
2. Shuying Zhao, Shibing Wang, Chenglong Qiu, Zaixiang Xu, Linhan Ren, Yuhang Wang, Suiqin Li, Jiahui He, Kai Li, Yinjie Xu, Mengxin Wang, Xing Zhong, Jianguo Wang. (2024) Enhanced electrocatalytic alcohol oxidation mediated with ultra-low concentration of aminoxyl radicals via an Intermediate-Rich local microenvironment. CHEMICAL ENGINEERING SCIENCE, 286 (119653). [10.1016/j.ces.2023.119653]
3. Jing-Jing Liu, Zhan-Yi Wang, Bin-Bin Jiang, Shu-Qin Gao, Ying-Wu Lin. (2023) Protective effect of thymoquinone on glycation of human myoglobin induced by d-ribose. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 253 (7): (127016). [PMID:37741485] [10.1016/j.ijbiomac.2023.127016]
4. Shilei Wang, Yuan Peng, Yixin Zhuang, Nan Wang, Jianchang Jin, Zhajun Zhan. (2023) Purification, Structural Analysis and Cardio-Protective Activity of Polysaccharides from Radix Astragali. MOLECULES, 28 (10): (4167). [PMID:37241906] [10.3390/molecules28104167]
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溶液计算器

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