Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
宿主种属
兔(Rabbit)
特异性
Bax
种属反应性
人(Human),仓鼠(Hamster),大鼠(Rat),小鼠(Mouse)
免疫原
A synthetic peptide derived from human BAX (AA 5-40).
阳性对照
WB: HeLa, HEK293, MCF7, SH-SY5Y, RAW 264.7 and C6 cell lysates. IHC: Human lung adenocarcinoma tissue.
Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
图片
Recombinant Bax Antibody (Ab090655) - Western Blot All lanes: Recombinant Bax Antibody (Ab090655) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution Predicted band size: 21 kDa Observed band size: 21 kDa Exposure time: 36.5 s
Recombinant Bax Antibody (Ab090655) - IHC Immunohistochemical analysis of paraffin-embedded Human lung adenocarcinoma, using Recombinant Bax Antibody (Ab090655) at 1/200 dilution.
ZJ25F0521907
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