Rabbit anti Human RNF40 Antibody, Recombinant, could be used for WB and so on. Application: WB: 1/500-1/1000 Protein Function: E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). Forms a ubiquitin ligase complex in cooperation with the E2 enzyme UBE2E1/UBCH6. It thereby plays a central role in histone code and gene regulation. Required for transcriptional activation of Hox genes.
规格
产品名称
Recombinant RNF40 Antibody
别名
RNF40抗体 | 环指蛋白40抗体 | 重组 RNF40 抗体
英文别名
95 kDa retinoblastoma-associated protein | BRE1-B | EC 2.3.2.27 | RBP95 | RING finger protein 40 | RING-type E3 ubiquitin transferase BRE1B | 95 kDa retinoblastoma associated protein antibody | 95 kDa retinoblastoma protein binding protein antibody | 95 k
规格或纯度
ExactAb™, Validated, 重组, 1.5 mg/mL
宿主种属
兔(Rabbit)
特异性
RNF40
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
A synthetic peptide derived from human RNF40 (AA 220-450)
Recombinant RNF40 Antibody (Ab125589) - Western Blot All lanes: Recombinant RNF40 Antibody (Ab125589) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 114 kDa Observed band size: 130 kDa Exposure time: 30.0 s