Rabbit anti Human SATB2 Antibody, Recombinant (MyR1-SATB2), could be used for IHC and so on. Application IHC: 1/100-1/200 Protein Function Binds to DNA, at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcription factor controlling nuclear gene expression, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Required for the initiation of the upper-layer neurons (UL1) specific genetic program and for the inactivation of deep-layer neurons (DL) and UL2 specific genes, probably by modulating BCL11B expression. Repressor of Ctip2 and regulatory determinant of corticocortical connections in the developing cerebral cortex. May play an important role in palate formation. Acts as a molecular node in a transcriptional network regulating skeletal development and osteoblast differentiation.
规格
产品名称
Recombinant SATB2 Antibody
别名
DNA结合蛋白2单克隆抗体 | 重组 SATB2 抗体
英文别名
DNA binding protein SATB2 antibody | DNA-binding protein SATB2 antibody | FLJ21474 antibody | FLJ32076 antibody | GLSS antibody | KIAA1034 antibody | MGC119474 antibody | MGC119477 antibody | SATB family member 2 antibody | SATB homeobox 2 antibody | SATB
Recombinant SATB2 Antibody (Ab126637) - IHC Immunohistochemistry analysis of paraffin-embedded human Vermiform appendix tissue labelling SATB2 with Recombinant SATB2 Antibody (Ab126637) at 1/100 dilution. The section was incubated with Ab126637 for 30 mins at room temperature. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 was used for antigen retrieval.