Rabbit anti Human SATB2 Antibody, Recombinant, could be used for WB, IHC, ICC, IF and so on. Application: WB: 1/500-1/2000 IHC: 1/50-1/200 ICC/IF: 1/50-1/200 Protein Function: Binds to DNA, at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcription factor controlling nuclear gene expression, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Required for the initiation of the upper-layer neurons (UL1) specific genetic program and for the inactivation of deep-layer neurons (DL) and UL2 specific genes, probably by modulating BCL11B expression. Repressor of Ctip2 and regulatory determinant of corticocortical connections in the developing cerebral cortex. May play an important role in palate formation. Acts as a molecular node in a transcriptional network regulating skeletal development and osteoblast differentiation.
Binds to DNA, at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcription factor controlling nuclear gene expression, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Required for the initiation of the upper-layer neurons (UL1) specific genetic program and for the inactivation of deep-layer neurons (DL) and UL2 specific genes, probably by modulating BCL11B expression. Repressor of Ctip2 and regulatory determinant of corticocortical connections in the developing cerebral cortex. May play an important role in palate formation. Acts as a molecular node in a transcriptional network regulating skeletal development and osteoblast differentiation.
宿主种属
兔(Rabbit)
特异性
SATB2
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
A synthetic peptide derived from human SATB2 (AA 220-280).
阳性对照
WB: HEK293, K562 and NIH/3T3 cell lysates. IHC: Human testis cancer, cervical cancer, stomach cancer tissues. ICC/IF: HeLa, SH-SY5Y cells.
Recombinant SATB2 Antibody (Ab126636) - Western Blot All lanes: Recombinant SATB2 Antibody (Ab126636) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/10000 dilution
Predicted band size: 83 kDa Observed band size: 97 kDa Exposure time: 98.2 s
Recombinant SATB2 Antibody (Ab126636) - IF/ICC Immunofluorescent analysis of HeLa cells, using Recombinant SATB2 Antibody (Ab126636) at 1/50 dilution.
Recombinant SATB2 Antibody (Ab126636) - IF/ICC Immunofluorescent analysis of SH-SY5Y cells, using Recombinant SATB2 Antibody (Ab126636).
Recombinant SATB2 Antibody (Ab126636) - IHC Immunohistochemical analysis of paraffin-embedded Human stomach cancer, using Recombinant SATB2 Antibody (Ab126636).
Recombinant SATB2 Antibody (Ab126636) - IHC Immunohistochemical analysis of paraffin-embedded Human testis cancer, using Recombinant SATB2 Antibody (Ab126636) at 1/100 dilution.
Recombinant SATB2 Antibody (Ab126636) - IHC Immunohistochemical analysis of paraffin-embedded Human cervical cancer, using Recombinant SATB2 Antibody (Ab126636) at 1/100 dilution.