ExactAb™,PBS Only,低内毒素,已验证,无动物源,无叠氮钠,无载体,重组 级 提供 ≥95%(SDS-PAGE&SEC-HPLC) 纯度，适用于对基线干扰要求严格的色谱和分析工作流程。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
Depatuxizumab mafodotin (anti-EGFR) 是一种抗体-药物偶联物，由 EGFR IGg1 单克隆抗体通过稳定的马来酰亚胺己酰基连接与微管蛋白抑制剂单甲基 auristatin F 偶联组成。Depatuxizumab mafodotin (anti-EGFR) 用于治疗复发性 EGFR 扩增的胶质母细胞瘤 (GBM)。
Depatuxizumab mafodotin (anti-EGFR) is an antibody-drug conjugate consisting of an EGFR IGg1 monoclonal antibody conjugated to the tubulin inhibitor monomethyl auristatin F via a stable maleimidocaproyl link. Depatuxizumab mafodotin (anti-EGFR) is used in the treatment of recurrent EGFR-amplified Glioblastoma (GBM).
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg
Depatuxizumab mafodotin (anti-EGFR) (Ab175508) - Flow Cytometry
Flow Cytometry analysis of A431 cells labelling EGFR (red) with Depatuxizumab mafodotin (anti-EGFR) (Ab175508). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Depatuxizumab mafodotin (anti-EGFR) (Ab175508) - ELISA
Immobilized EGFR-chis at 2 μg/mL can bind Depatuxizumab mafodotin (anti-EGFR) (Ab175508) with the EC₅₀ of 19.05 ng/mL.
Depatuxizumab mafodotin (anti-EGFR) (Ab175508) - Flow Cytometry
Flow Cytometry analysis of Hela cells labelling EGFR (red) with Depatuxizumab mafodotin (anti-EGFR) (Ab175508). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Depatuxizumab mafodotin (anti-EGFR) (Ab175508) - Flow Cytometry
Flow Cytometry analysis of A549 cells labelling EGFR (red) with Depatuxizumab mafodotin (anti-EGFR) (Ab175508). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Depatuxizumab mafodotin (anti-EGFR) (Ab175508) - SEC
The purity of Depatuxizumab mafodotin (anti-EGFR) (Ab175508) is more than 95% verified by HPLC.
Depatuxizumab mafodotin (anti-EGFR) (Ab175508) - ELISA
Immobilized Recombinant Human EGFR protein (rp176273) at 1.0 μg/mL can bind Depatuxizumab mafodotin (anti-EGFR) (Ab175508) with the EC50 of 28.96 ng/mL.
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
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通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！
| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
 ZJ24F0102634 |
分析证书 | Ab175508 |
| ZJ24F0102635 |
分析证书 | Ab175508 |
| ZJ24F0102636 |
分析证书 | Ab175508 |
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