ExactAb™,低内毒素,已验证,无动物源,无叠氮钠,无载体,重组 级 提供 ≥95%(SDS-PAGE&SEC-HPLC) 纯度，适用于对基线干扰要求严格的色谱和分析工作流程。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
Mezagitamab (anti-CD38) 是一种 IgG1λ 抗 CD38 的单克隆抗体。Mezagitamab (anti-CD38) 通过抗体和补体依赖性细胞毒性耗尽表达 CD38 的肿瘤细胞。Mezagitamab (anti-CD38) 在复发/难治性多发性骨髓瘤 (RRMM) 和原发性血小板减少性紫癜 (ITP) 中有潜在应用。
Mezagitamab (anti-CD38) is a IgG1λ anti-CD38 monoclonal antibody. Mezagitamab (anti-CD38) depletes tumor cells expressing CD38 through antibody and complement dependent cytotoxicity. Mezagitamab (anti-CD38) has potential application in relapsed/refractory multiple myeloma (RRMM) and idiopathic thrombocytopenic purpura (ITP).
Mezagitamab (anti-CD38) (Ab175597) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling DPP4 with Mezagitamab (anti-CD38) (Ab175597) conjugated with biotin (right panel) compared with Human IgG (Ab170213) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156150).
Mezagitamab (anti-CD38) (Ab175597) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling DPP4 (red) with Mezagitamab (anti-CD38) (Ab175597) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, human IgG (Ab170213) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.
Mezagitamab (anti-CD38) (Ab175597) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling CD38 (red) with Mezagitamab (anti-CD38) (Ab175597). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Mezagitamab (anti-CD38) (Ab175597) - SEC
The purity of Mezagitamab (anti-CD38) (Ab175597) is more than 95% verified by HPLC.
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
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| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
 ZJ24F1113323 |
分析证书 | Ab175597 |
| ZJ24F1113324 |
分析证书 | Ab175597 |
| ZJ24F1113325 |
分析证书 | Ab175597 |
| ZJ24F0303100 |
分析证书 | Ab175597 |
| ZJ24F0303101 |
分析证书 | Ab175597 |
| ZJ24F0303102 |
分析证书 | Ab175597 |
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