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药物发现
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Recombinant Human IL-6R Protein
- 种属: 人(Human)
- Accession #: P08887
- 表达系统: HEK293
- 蛋白标签: C-His
- 内毒素水平: <1.0 EU/μg
- 生物活性: 1. Immobilized Recombinant Human IL-6 Protein at 2 μg/mL can bind Recombinant Human IL-6R Protein (rp147628) the EC50 is 8.0 - 24.0 ng/mL. 2. Measured by its ability to enhance the IL-6 activity on M1 mouse myeloid leukemia cells. The ED50 for this effect is typically 10.0 - 60.0 ng/mL.3. Using the Octet RED System, the affinity constant (Kd) of Recombinant Human IL-6R Protein (rp147628) bound Anti-IL6R Antibody was 0.1 nM.
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Recombinant Human Clusterin Protein
- 种属: 人(Human)
- Accession #: P10909-1
- 表达系统: HEK293
- 蛋白标签: C-His
- 内毒素水平: <0.1 EU/μg
- 生物活性: Measured by its ability to induce clustering of Caki‑2 human clear cell carcinoma epithelial cells.
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Recombinant Human NCAM-1/CD56 Protein
- 种属: 人(Human)
- Accession #: P13591
- 表达系统: CHO
- 蛋白标签: C-His
- 内毒素水平: <1.0 EU/μg
- 生物活性: Testing in progress
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Recombinant human BACE1 protein
- 种属: 人(Human)
- Accession #: P56817-1
- 表达系统: HEK293
- 蛋白标签: C-His
- 内毒素水平: <0.1 EU/μg
- 生物活性: Measured by its ability to cleave a fluorogenic peptide substrate, Mca-SEVNLDAEFRK(Dpn)RR-NH2. The specific activity is >5.5 pmol/min/μg.
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Recombinant Human Arginase 1/ARG1 Protein
- 种属: 人(Human)
- Accession #: P05089-1
- 表达系统: HEK293
- 蛋白标签: C-His
- 内毒素水平: <0.1 EU/μg
- 生物活性: Measured by the production of urea during the hydrolysis of arginine. The specific activity is >27833 pmol/min/μg.
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Recombinant Human ErbB2/HER2 Protein
- 种属: 人(Human)
- Accession #: P04626
- 表达系统: HEK293
- 蛋白标签: C-His
- 内毒素水平: <1.0 EU/μg
- 生物活性: Pertuzumab (anti-HER2) (P412000) at 1.0 ug/mL can bind biotinylated Human ErbB2/HER2 Protein (rp169607), The EC50 for this effect is 25.99 ng/mL.
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Recombinant Human 4-1BB/TNFRSF9 Protein
- 种属: 人(Human)
- Accession #: Q07011
- 表达系统: HEK293
- 蛋白标签: C-His
- 内毒素水平: <1.0 EU/μg
- 生物活性: Measured by its binding ability in a functional ELISA. Human 4-1BB/TNFRSF9 (rp169624) at 1.0 μg/mL can bind Urelumab (anti-TNFRSF9) (Ab170654) with the EC50 of 47.08 ng/mL.
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Recombinant Bovine CD4 Protein
- 种属: 牛(Bovine)
- Accession #: F1MJK4
- 表达系统: HEK293
- 蛋白标签: C-His
- 内毒素水平: <1.0 EU/μg
- 生物活性: Measured by the ability of the immobilized protein to support the adhesion of NIH‑3T3 mouse embryonic fibroblast cells.The ED50for this effect is 0.1-0.5 μg/mL after a 1 hour incubation at37 °C.Optimal dilutions should be determined by each laboratory for each application.
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Recombinant Feline CD56 Protein
- 种属: 猫(Feline)
- Accession #: Q5G7G8
- 表达系统: HEK293
- 蛋白标签: C-His
- 内毒素水平: <1.0 EU/μg
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Recombinant Human Siglec-2/CD22 Protein
- 种属: 人(Human)
- Accession #: P20273
- 表达系统: HEK293
- 蛋白标签: C-His
- 内毒素水平: <1.0 EU/μg
- 生物活性: Immobilized Recombinant Human Siglec-2/CD22 Protein (rp169575) at 1.0 μg/mL can bind Inotuzumab (anti-CD22) (Ab176429) with the EC50 of 20.1 ng/mL. Immobilized Recombinant Human Siglec-2/CD22 Protein (rp169575) at 1.0 μg/mL can bind bind Epratuzumab (anti-CD22) (Ab175532) with the EC50 of 207.0 ng/mL.
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Recombinant Human BCMA/TNFRSF17 Protein
- 种属: 人(Human)
- Accession #: Q6PE46
- 表达系统: HEK293
- 蛋白标签: C-hFc
- 内毒素水平: <1.0 EU/μg
- 生物活性: Immobilized Recombinant Human BCMA/TNFRSF17 Protein (rp169554) at 0.5 μg/mL can bind Belantamab (anti-TNFRSF17) (Ab170526) with the EC50 of 22.0 ng/mL.
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Recombinant Human Glypican 3 Protein
- 种属: 人(Human)
- Accession #: P51654-1
- 表达系统: HEK293
- 蛋白标签: C-His
- 内毒素水平: <1.0 EU/μg
- 生物活性: Immobilized Recombinant Human Glypican 3 Protein (rp176299) at 4.0 μg/mL can bind Recombinant Human FGF basic Protein (rp156010) with the EC50 of 441.4 ng/mL. Immobilized Recombinant Human FGF basic Protein (rp156010) at 1.0 μg/mL can bind Recombinant Human Glypican 3 Protein (rp176299) with the EC50 of 7.4 ng/mL.
