ExactAb™,低内毒素,已验证,无动物源,无叠氮钠,无载体,重组 级 提供 ≥95%(SDS-PAGE&SEC-HPLC) 纯度，适用于对基线干扰要求严格的色谱和分析工作流程。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
Muromonab (anti-CD3) 是一种靶向 CD3 抗原的鼠源 IgG2a mAb。Muromonab (anti-CD3) 特异性结合人类和高等灵长类动物的 T 细胞表面 CD3 抗原。Muromonab (anti-CD3) 可阻断 T 细胞受体识别外来抗原的功能，抑制 T 细胞介导的免疫反应，包括细胞介导的淋巴细胞溶解和 T 细胞增殖反应。Muromonab (anti-CD3) 可用于研究急性肾、肝、心脏和联合肾脏-胰腺移植排斥反应，还可用于研究骨髓移植患者的移植物抗宿主病。
Muromonab (anti-CD3) is a mouse monoclonal antibody targeting the CD3 antigen. Muromonab (anti-CD3) specifically binds to the CD3 antigen on the surface of human and higher primate T cells. Muromonab (anti-CD3) blocks the function of T cell receptors to recognize foreign antigens and inhibits T cell-mediated immune responses, including cell-mediated lymphocyte lysis and T cell proliferation responses. Muromonab (anti-CD3) can be used to study acute kidney, liver, heart and combined kidney-pancreas transplant rejection, and can also be used to study graft-versus-host disease in bone marrow transplant patients.
Muromonab (anti-CD3) (Ab170491) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD3 with Muromonab (anti-CD3) (Ab170491) (right panel) conjugated with biotin compared with Human IgG (Ab170213) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156150).
Muromonab (anti-CD3) (Ab170491) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD3 (red) with Muromonab (anti-CD3) (Ab170491) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, human IgG (Ab170213) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.
Muromonab (anti-CD3) (Ab170491) - Flow Cytometry
Flow Cytometry analysis of Jurkat cells labelling CD3 (red) with Muromonab (anti-CD3) (Ab170491). Goat Anti-Human IgG (FITC) (Ab175834) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Muromonab (anti-CD3) (Ab170491) - SEC
The purity of Muromonab (anti-CD3) (Ab170491) is more than 95% verified by HPLC.
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
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通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！
| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
 ZJ24F0708072 |
分析证书 | Ab170491 |
| ZJ23F1001371 |
分析证书 | Ab170491 |
| ZJ23F1001372 |
分析证书 | Ab170491 |
| ZJ26F0636103 |
分析证书 | Ab170491 |
| ZJ26F0737975 |
分析证书 | Ab170491 |
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