计算溶液所需的质量、体积或浓度。
PROTAC KRAS G12C degrader-1 is a Cereblon -based KRAS G12C PROTAC degrader. PROTAC KRAS G12C degrader-1 induces CRBN/ KRAS G12C dimerization and degrades GFP- KRAS G12C in reporter cells.
Appearance:Solid
In Vitro:PROTAC KRAS G12C degrader-1 (Compound 10) engages CRBN in cells, bound KRASG12C in vitro, induces CRBN/KRASG12C dimerization, and degrades GFP-KRASG12C in reporter cells in a CRBN-dependent manner. MCE has not independently confirmed the accuracy of
Biological Activity:PROTAC KRAS G12C degrader-1 is a Cereblon -based KRAS G12C PROTAC degrader. PROTAC KRAS G12C degrader-1 induces CRBN/ KRAS G12C dimerization and degrades GFP- KRAS G12C in reporter cells.