Immobilized Recombinant Human EGFR Protein (rp176273) at 1.0 μg/mL can bind Depatuxizumab (anti-EGFR) (Ab182750) with the EC50 of 25.83 ng/mL. Immobilized Recombinant Human EGFR Protein (rp176273) at 1.0 μg/mL can bind Depatuxizumab mafodotin (anti-EGFR) (Ab175508) with the EC50 of 28.96 ng/mL. Immobilized Recombinant Human EGFR Protein (rp176273) at 1.0 μg/mL can bind Nimotuzumab (anti-EGFR) (Ab175612) with the EC50 of 45.18 ng/mL. Immobilized Recombinant Human EGFR Protein (rp176273) at 1.0 μg/mL can bind Serclutamab (anti-EGFR) (Ab182867) with the EC50 of 35.7 ng/mL. Immobilized Recombinant Human EGFR Protein (rp176273) at 1.0 μg/mL can bind Cetuximab (anti-EGFR) (C411992) with the EC50 of 17.44 ng/mL. Immobilized Recombinant Human EGFR Protein (rp176273) at 1.0 μg/mL can bind Panitumumab (anti-EGFR) (Ab169317) with the EC50 of 23.66 ng/mL.
Protein Function： As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently.
规格
产品名称
Recombinant Human EGFR Protein
别名
重组人EGFR蛋白 | 重组人表皮生长因子受体 | 重组人 EGFR 蛋白
英文别名
cell growth inhibiting protein 40 | avian erythroblastic leukemia viral (v-erb-b) oncogene homolog | cell proliferation-inducing protein 61 | EC 2.7.10 | EC 2.7.10.1 | EGF R | EGFR | epidermal growth factor receptor (avian erythroblastic leukemia viral (v
Immobilized Recombinant Human EGFR Protein (rp176273) at 1.0 μg/mL can bind Depatuxizumab (anti-EGFR) (Ab182750) with the EC50 of 25.83 ng/mL. Immobilized Recombinant Human EGFR Protein (rp176273) at 1.0 μg/mL can bind Depatuxizumab mafodotin (anti-EGFR) (Ab175508) with the EC50 of 28.96 ng/mL. Immobilized Recombinant Human EGFR Protein (rp176273) at 1.0 μg/mL can bind Nimotuzumab (anti-EGFR) (Ab175612) with the EC50 of 45.18 ng/mL. Immobilized Recombinant Human EGFR Protein (rp176273) at 1.0 μg/mL can bind Serclutamab (anti-EGFR) (Ab182867) with the EC50 of 35.7 ng/mL. Immobilized Recombinant Human EGFR Protein (rp176273) at 1.0 μg/mL can bind Cetuximab (anti-EGFR) (C411992) with the EC50 of 17.44 ng/mL. Immobilized Recombinant Human EGFR Protein (rp176273) at 1.0 μg/mL can bind Panitumumab (anti-EGFR) (Ab169317) with the EC50 of 23.66 ng/mL.
99.6 kDa, under reducing conditions; 99.6 kDa, under non-reducing conditions
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
冻干(Lyophilized)
储存缓冲液
Lyophilized from PBS, pH 7.4
复溶
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
在 -20°C 下可保存 1 年。避免冷冻/解冻循环。
图片
Recombinant Human EGFR Protein (rp176273) - ELISA Immobilized Recombinant Human EGFR Protein (rp176273) at 1.0 μg/mL can bind Depatuxizumab (anti-EGFR) (Ab182750) with the EC₅₀ of 25.83 ng/mL.
Recombinant Human EGFR Protein (rp176273) - ELISA Immobilized Recombinant Human EGFR Protein (rp176273) at 1.0 μg/mL can bind Depatuxizumab mafodotin (anti-EGFR) (Ab175508) with the EC50 of 28.96 ng/mL.
Recombinant Human EGFR Protein (rp176273) - ELISA Immobilized Recombinant Human EGFR Protein (rp176273) at 1.0 μg/mL can bind Nimotuzumab (anti-EGFR) (Ab175612) with the EC₅₀ of 45.18 ng/mL.
Recombinant Human EGFR Protein (rp176273) - ELISA Immobilized Recombinant Human EGFR Protein (rp176273) at 1.0 μg/mL can bind Serclutamab (anti-EGFR) (Ab182867) with the EC₅₀ of 35.7 ng/mL.
Recombinant Human EGFR Protein (rp176273) - ELISA Immobilized Recombinant Human EGFR Protein (rp176273) at 1.0 μg/mL can bind Cetuximab (anti-EGFR) (C411992) with the EC₅₀ of 17.44 ng/mL.
Recombinant Human EGFR Protein (rp176273) - ELISA Immobilized Recombinant Human EGFR Protein (rp176273) at 1.0 μg/mL can bind Panitumumab (anti-EGFR) (Ab169317) with the EC₅₀ of 23.66 ng/mL.
Recombinant Human EGFR Protein (rp176273) - SDS-PAGE 2 μg/lane of Recombinant Human EGFR Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 99.6 kDa.
ZJ24F0809259
危险品化学品经营许可证（带存储）