LGALS3 (Galectin 3) is a Protein Coding gene. This gene encodes a member of the galectin family of carbohydrate-binding proteins. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. LGALS3 is a beta-galactoside-binding lectin and plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion, and T-cell regulation. LGALS3 has an important role in tumor progression through inhibition of apoptosis. LGALS3 expression is associated with neoplastic transformation and with differentiation of monocytes to macrophages. Elevated expression of LGALS3 has been demonstrated in the synovium of rheumatoid arthritis (RA). Diseases associated with LGALS3 include Follicular Adenoma and Papillary Carcinoma.
生物活性
Measured by its ability to agglutinate human red blood cells. The ED50 for this effect is <5.0 µg/mL.
29.0 kDa, under reducing conditions; 29.0 kDa, under non-reducing conditions.
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
冻干(Lyophilized)
储存缓冲液
Lyophilized from PBS, pH 7.4.
复溶
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 0.1 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
Store at -20°C for 1 year. Avoid freeze/thaw cycle.
图片
Recombinant Human Galectin-3 Protein (rp179829) - Protein Bioactivity Measured by its ability to agglutinate human red blood cells. The ED₅₀ for this effect is < 5.0 µg/mL.
Recombinant Human Galectin-3 Protein (rp179829) - SDS-PAGE 3 μg/lane of Recombinant Human Galectin-3 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 29.0 kDa.
Recombinant Human Galectin-3 Protein (rp179829) - Binding Activity Immobilized Recombinant Human Galectin-3 Protein (rp179829) at 5.0 μg/mL can bind Recombinant Human CD107a Protein (rp214422) with the EC50 of 3.5 μg/mL.