N-乙酰-D-氨基葡萄糖

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A118965-5g
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A118965-500g
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A118965-2.5kg
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糖合成砌块 (6) 葡糖胺 (5)

基本描述

别名 N-乙酰氨基葡萄糖 | 2-乙酰氨基-2-脱氧-D-葡萄糖
英文别名 D-GlcNAc | 2-Acetamido-2-deoxy-D-glucose
规格或纯度 用于细胞培养, ≥98%
英文名称 N-Acetyl-D-glucosamine
生化机理 N-乙酰氨基葡萄糖(GlcNAc)低聚物可能具有体内启动犬多形核细胞(PMN)因子的能力。它具有伤口愈合和趋化活性。GlcNAc及其衍生物常用于制备膳食补充剂,也用于治疗制剂开发
储存温度 -20°C储存,充氩
运输条件 超低温冰袋运输
产品介绍

N-乙酰氨基葡萄糖(GlcNAc)是葡萄糖的衍生物,同时是一种单糖。这是一种白色粉末,略带甜味。其熔点为221°C。 GlcNAc可25%溶于水。它存在于植物的菠萝蛋白酶、蓖麻蛋白凝集素和鸥属凝集素中。在人类体内,它存在于组织纤溶酶原活化剂、生长因子和激素中 

应用:

用作形成斑点印迹的底物;用作免疫组织化学分析中的反向碱性磷酸酶的底物;在免疫印迹分析中检测特定免疫复合物

N-Acetylglucosamine (GlcNAc), a derivative of glucose is a monosaccharide. It is a white powder and is mildly sweet. It melts at 221°C. GlcNAc is 25% soluble in water. It is present in bromelain, ricin agglutinin and abrus agglutinin, in plants. In humans, it is present in tissue plasminogen activator, growth factors and hormones.

AI解读

关联靶点(其它种属)

Hdac6 Histone deacetylase 6 (222 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SARS-CoV-2 (38078 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

PubChem SID 504760627
EC号 231-368-2
分子类型 小分子
Canonical SMILES CC(=O)N[C@@H](C=O)[C@H]([C@@H]([C@@H](CO)O)O)O
Isomeric SMILES CC(=O)N[C@@H](C=O)[C@H]([C@@H]([C@@H](CO)O)O)O
WGK Germany 3
PubChem CID 1738118
分子量 221.21
Beilstein号 1727589
Reaxy-Rn 1913592

化学和物理性质

溶解性 可溶于水
密度 1
敏感性 易吸潮
比旋光度 +39.0 to +43.0 deg(C=1, H2O)
熔点 211°C
分子量 221.210 g/mol
XLogP3 -3.400
氢键供体数Hydrogen Bond Donor Count 5
氢键受体数Hydrogen Bond Acceptor Count 6
可旋转键计数Rotatable Bond Count 6
精确质量Exact Mass 221.09 Da
单同位素质量Monoisotopic Mass 221.09 Da
拓扑极表面积Topological Polar Surface Area 127.000 Ų
重原子数Heavy Atom Count 15
形式电荷Formal Charge 0
复杂度Complexity 221.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 4
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性(GHS)

WGK Germany 3
Reaxy-Rn 1913592
个人防护装备 Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

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B2525126 分析证书 25-01-04 A118965
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G2214073 分析证书 22-06-14 A118965

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