Rabbit anti Human CHMP2B Antibody, Recombinant, could be used for WB and so on. Application WB: 1/500-1/1000 Protein Function Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4.
规格
产品名称
Recombinant CHMP2B Antibody
别名
染色质修饰蛋白2B重组兔单克隆抗体 | 重组 CHMP2B 抗体
英文别名
ALS17 antibody | Charged multivesicular body protein 2b antibody | CHM2B_HUMAN antibody | CHMP family, member 2B antibody | CHMP2.5 antibody | CHMP2b antibody | Chromatin modifying protein 2b antibody | Chromatin-modifying protein 2b antibody | DMT1 antib
规格或纯度
ExactAb™, Validated, 重组, 0.4 mg/mL
宿主种属
兔(Rabbit)
特异性
CHMP2B
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
A synthetic peptide derived from human CHMP2B (AA 171-213)
Recombinant CHMP2B Antibody (Ab096362) - Western Blot All lanes: Recombinant CHMP2B Antibody (Ab096362) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 24 kDa Observed band size: 30 kDa Exposure time: 1.1 s