Rabbit anti Human CPEB1 Antibody, Recombinant, could be used for WB and so on. Application: WB: 1/500-1/2000 Protein Function Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA; a repression that is relieved by phosphorylation or degradation (By similarity). Involved in the transport of CPE-containing mRNA to dendrites; those mRNAs may be transported to dendrites in a translationally dormant form and translationally activated at synapses (By similarity). Its interaction with APLP1 promotes local CPE-containing mRNA polyadenylation and translation activation (By similarity). Induces the assembly of stress granules in the absence of stress.
规格
产品名称
Recombinant CPEB1 Antibody
别名
细胞质多聚腺苷酸结合蛋白1抗体 | 重组CPEB1抗体
英文别名
CPE-binding protein 1 | CPE-BP1 | CPEB 1 | CPEB | CPEB1 | CPEB1 protein | CPEB1_HUMAN | Cytoplasmic polyadenylation binding protein 1 | Cytoplasmic polyadenylation element binding protein | Cytoplasmic polyadenylation element binding protein 1 | Cytoplasm
规格或纯度
重组, ExactAb™, 已验证, 见COA
宿主种属
兔(Rabbit)
特异性
CPEB1
种属反应性
人(Human)
预测反应种属
苏门答腊猩猩(Sumatran orangutan)
免疫原
A synthesized peptide derived from human CPEB1 (AA 265-325)
Recombinant CPEB1 Antibody (Ab097517) - Western Blot All lanes: Recombinant CPEB1 Antibody (Ab097517) at 1/2000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 63 kDa Observed band size: 68 kDa Exposure time: 26.0 s