Rabbit anti Human Drosha Antibody, Recombinant, could be used for WB and so on. Application WB: 1/500-1/1000 Protein Function Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DROSHA cleaves the 3' and 5' strands of a stem-loop in pri-miRNAs (processing center 11 bp from the dsRNA-ssRNA junction) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. Involved also in pre-rRNA processing. Cleaves double-strand RNA and does not cleave single-strand RNA. Involved in the formation of GW bodies.
规格
产品名称
Recombinant Drosha Antibody
别名
核糖核酸酶3重组兔单克隆抗体 | 核糖核酸酶3重组兔单克隆抗体 | 重组Drosha抗体
英文别名
DROSHA antibody | Drosha double stranded RNA specific endoribonuclease antibody | Drosha ribonuclease type III antibody | Etohi2 antibody | HSA242976 antibody | Nuclear RNase III Drosha antibody | p241 antibody | Protein Drosha antibody | Putative protein
规格或纯度
ExactAb™, Validated, 重组, 1.0 mg/mL
宿主种属
兔(Rabbit)
特异性
Drosha
种属反应性
人(Human)
免疫原
A synthetic peptide derived from human Drosha (AA 20-77)
Recombinant Drosha Antibody (Ab100514) - Western Blot All lanes: Recombinant Drosha Antibody (Ab100514) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/30000 dilution Predicted band size: 159 kDa Observed band size: 170 kDa Exposure time: 114.2 s