Rabbit anti Human E2F6 Antibody, Recombinant, could be used for WB and so on. Application: WB: 1/500-1/2000 Protein Function Inhibitor of E2F-dependent transcription. Binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Has a preference for the 5'-TTTCCCGC-3' E2F recognition site. E2F-6 lacks the transcriptional activation and pocket protein binding domains. Appears to regulate a subset of E2F-dependent genes whose products are required for entry into the cell cycle but not for normal cell cycle progression. May silence expression via the recruitment of a chromatin remodeling complex containing histone H3-K9 methyltransferase activity. Overexpression delays the exit of cells from the S-phase.
规格
产品名称
Recombinant E2F6 Antibody
别名
转录因子E2F6抗体 | 重组E2F6抗体
英文别名
E2F binding site modulating activity protein | E2F transcription factor 6 | E2F transcription factor 6 isoform 1 | EMA | MGC111545 | Transcription factor E2F6 | E2F6_HUMAN | E2F 6 antibody | E2F 6 | E2F binding site modulating activity protein antibody |
规格或纯度
重组, ExactAb™, 已验证, 见COA
宿主种属
兔(Rabbit)
特异性
E2F6
种属反应性
人(Human)
免疫原
A synthetic peptide derived from human E2F6 (AA 100-281)
Recombinant E2F6 Antibody (Ab100799) - Western Blot All lanes: Recombinant E2F6 Antibody (Ab100799) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 32 kDa Observed band size: 32 kDa Exposure time: 100.0 s