Rabbit anti Human EYA2 Antibody, Recombinant, could be used for WB and so on. Application: WB: 1/1000-1/50000 Protein Function Tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. Coactivates SIX1. Seems to coactivate SIX2, SIX4 and SIX5. Together with SIX1 and DACH2 seem to be involved in myogenesis. May be involved in development of the eye. Interaction with GNAZ and GNAI2 prevents nuclear translocation and transcriptional activity.
规格
产品名称
Recombinant EYA2 Antibody
别名
眼睛发育缺失蛋白EYA2抗体 | 眼睛发育缺失蛋白EYA2抗体 | 重组EYA2抗体
英文别名
EAB 1 | EAB1 | EYA 2 | EYA2 | EYA2_HUMAN | eyes absent 2 homolog (Drosophila) | Eyes absent homolog 2 | Translation of this uORF probably lowers the translation efficiency of EYA2 | EAB 1 antibody | EAB1 antibody | EYA 2 antibody | EYA transcriptional coa
规格或纯度
ExactAb™, Validated, Recombinant, High performance, 0.6 mg/mL
宿主种属
兔(Rabbit)
特异性
EYA2
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
A synthetic peptide derived from human EYA2 (AA 28-40)
Recombinant EYA2 Antibody (Ab102536) - Western Blot All lanes: Recombinant EYA2 Antibody (Ab102536) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution Predicted band size: 59 kDa Observed band size: 63 kDa Exposure time: 10.3 s