Rabbit anti Human GRIM19 Antibody, Recombinant, could be used for WB and so on. Application: WB: 1/500-1/2000 Protein Function Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Involved in the interferon/all-trans-retinoic acid (IFN/RA) induced cell death. This apoptotic activity is inhibited by interaction with viral IRF1. Prevents the transactivation of STAT3 target genes. May play a role in CARD15-mediated innate mucosal responses and serve to regulate intestinal epithelial cell responses to microbes.
规格
产品名称
Recombinant GRIM19 Antibody
别名
干扰素/维甲酸诱导凋亡相关基因抗体 | 重组GRIM19抗体
英文别名
Cell death regulatory protein | Cell death regulatory protein GRIM-19 | CGI-39 | CGI39 protein | CI-B16.6 | GRIM-19 | GRIM 19 | Complex I-B16.6 | CDA016 | Gene associated with retinoic and IFN-induced mortality 19 protein | Gene associated with retinoic a
规格或纯度
重组, ExactAb™, 已验证, 见COA
宿主种属
兔(Rabbit)
特异性
NDUFA13
种属反应性
人(Human)
预测反应种属
Bornean orangutan,大猩猩(Gorilla),黑猩猩(Chimpanzee)
免疫原
A synthetic peptide derived from human GRIM19 (AA 60-100)
阳性对照
WB: Ramos, Jurkat, HeLa, HEK293 and Hep G2 cell lysates.
Recombinant GRIM19 Antibody (Ab106432) - Western Blot All lanes: Recombinant GRIM19 Antibody (Ab106432) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution Predicted band size: 17 kDa Observed band size: 16 kDa Exposure time: 4.1 s