Rabbit anti Human hHR23A Antibody, Recombinant, could be used for WB and so on. Application: WB: 1/500-1/1000 Protein Function: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to 'Lys-48'-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to 'Lys-63'-linked polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. Involved in nucleotide excision repair and is thought to be functional equivalent for RAD23B in global genome nucleotide excision repair (GG-NER) by association with XPC. In vitro, the XPC:RAD23A dimer has NER activity. Can stabilize XPC. Involved in vpr-dependent replication of HIV-1 in non-proliferating cells and primary macrophages. Required for the association of HIV-1 vpr with the host proteasome.
规格
产品名称
Recombinant hHR23A Antibody
别名
hHR23A抗体 | 紫外切除修复蛋白RAD23A抗体 | 重组hHR23A抗体
英文别名
hHR23A | HR23A | hHR 23A antibody | hHR23A antibody | HR23A antibody | MGC111083 antibody | RAD 23a antibody | RAD23 homolog A (S. cerevisiae) antibody | RAD23 homolog A antibody | RAD23 yeast homolog A antibody | RAD23A antibody | RD23A_HUMAN antibody |
规格或纯度
ExactAb™, Validated, 重组, 0.2 mg/mL
宿主种属
兔(Rabbit)
特异性
hHR23A
种属反应性
人(Human)
免疫原
A synthetic peptide derived from human hHR23A (AA 207-220)
Recombinant hHR23A Antibody (Ab107440) - Western Blot All lanes: Recombinant hHR23A Antibody (Ab107440) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 40 kDa Observed band size: 32, 49 kDa Exposure time: 21.9 s