2610109B09Rik antibody | A930014B11Rik antibody | E130315I21Rik antibody | HIP 1 antibody | HIP I antibody | HIP-1 antibody | HIP-I antibody | hip1 antibody | HIP1/PDGFRB fusion gene antibody | HIP1/PDGFRB fusion gene, included antibody | HIP1_HUMAN antib
规格或纯度
重组,ExactAb™,已验证,见COA
生化机理
Plays a role in clathrin-mediated endocytosis and trafficking. Involved in regulating AMPA receptor trafficking in the central nervous system in an NMDA-dependent manner. Enhances androgen receptor (AR)-mediated transcription. May act as a proapoptotic protein that induces cell death by acting through the intrinsic apoptosis pathway. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis. May play a functional role in the cell filament networks. May be required for differentiation, proliferation, and/or survival of somatic and germline progenitors.
宿主种属
兔(Rabbit)
特异性
HIP1
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
A synthetic peptide derived from human HIP1 (AA 970-1037)
阳性对照
WB: Jurkat, HeLa, HEK293, SK-OV-3, NIH/3T3 and C6 cell lysates.
Recombinant HIP1 Antibody (Ab107535) - Western Blot All lanes: Recombinant HIP1 Antibody (Ab107535) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution Predicted band size: 116 kDa Observed band size: 117, 119 kDa Exposure time: 4.5 s
ZJ26F0535709
危险品化学品经营许可证（带存储）