Rabbit anti Human HLA DMB Antibody, Recombinant, could be used for WB and so on. Application: WB: 1/500-1/2000 Protein Relevance: HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.
规格
产品名称
Recombinant HLA DMB Antibody
别名
HLA DMB抗体 | 组织相容性复合体β抗体 | 重组HLA DMB抗体
英文别名
class II histocompatibility antigen antibody | Class II histocompatibility antigen M beta chain antibody | D6S221E antibody | DMB antibody | HLA class II histocompatibility antigen DM beta chain antibody | HLA-DM histocompatibility type, beta chain antibo
规格或纯度
重组, ExactAb™, 已验证, 见COA
宿主种属
兔(Rabbit)
特异性
HLA-DMB
种属反应性
人(Human)
免疫原
A synthetic peptide derived from human HLA DMB (AA 32-85).
Recombinant HLA DMB Antibody (Ab108179) - Western Blot All lanes: Recombinant HLA DMB Antibody (Ab108179) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/10000 dilution
Predicted band size: 29 kDa Observed band size: 30 kDa Exposure time: 33.5 s