Hu-antigen R | HuR | ELAV (embryonic lethal abnormal vision Drosophila) like 1 antibody | ELAV (embryonic lethal, abnormal vision, Drosophila) like 1 (Hu antigen R) antibody | ELAV like 1 antibody | ELAV like RNA binding protein 1 antibody | ELAV-like pro
规格或纯度
重组, ExactAb™, 已验证, 见COA
生化机理
Involved in 3'-UTR ARE-mediated MYC stabilization. Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, HUR binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA and AUUUUUA motifs.
宿主种属
兔(Rabbit)
特异性
HuR/ELAVL1
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
A synthetic peptide derived from human HuR / ELAVL1 (AA 52-96)
阳性对照
WB: Mouse heart, LNCaP, A549, Hep G2, MCF7, HeLa and HEK293 lysates.
Recombinant HuR/ELAVL1 Antibody (Ab109133) - Western Blot All lanes: Recombinant HuR/ELAVL1 Antibody (Ab109133) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution Predicted band size: 36 kDa Observed band size: 33 kDa Exposure time: 4.5 s
Recombinant HuR/ELAVL1 Antibody (Ab109133) - IF/ICC Immunofluorescent analysis of HeLa cells, using Recombinant HuR/ELAVL1 Antibody (Ab109133) at 1/50 dilution.