Rabbit anti Human KDM2A Antibody, Recombinant, could be used for WB and so on. Application: WB: 1/500-1/1000 Protein Function Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the centromere. Required to sustain centromeric integrity and genomic stability, particularly during mitosis.
规格
产品名称
Recombinant KDM2A Antibody
别名
FBXL11蛋白抗体 | 重组 KDM2A 抗体
英文别名
[Histone-H3]-lysine-36 demethylase 1A | CXXC-type zinc finger protein 8 | CXXC8 | F box / LRR repeat protein 11 | F box and leucine rich repeat protein 11 | F box protein FBL7 | F-box and leucine-rich repeat protein 11 | F-box protein FBL7 | F-box protein
规格或纯度
ExactAb™, Validated, 重组, 1.3 mg/mL
宿主种属
兔(Rabbit)
特异性
KDM2A
种属反应性
人(Human),小鼠(Mouse)
免疫原
A synthetic peptide derived from human FBXL11 (AA 2-19)
阳性对照
WB: Jurkat, HeLa, K562, MCF7 and NIH/3T3 cell lysates.
Recombinant KDM2A Antibody (Ab111919) - Western Blot All lanes: Recombinant KDM2A Antibody (Ab111919) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 133 kDa Observed band size: 138 kDa Exposure time: 28.9 s