Rabbit anti Human Langerin Antibody, Polyclonal, could be used for WB and so on. Application: WB: 1/500-1/2000 Protein Function Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation.
规格
产品名称
Langerin Antibody
别名
白细胞分化抗原CD207抗体 | 白细胞分化抗原CD207抗体 | Langerin 抗体
英文别名
C type lectin domain family 4 member K antibody | C-type lectin domain family 4 member K antibody | CD 207 antibody | CD207 antibody | CD207 antigen antibody | CD207 antigen, langerin antibody | CD207 molecule antibody | CLC4K_HUMAN antibody | CLEC 4K ant
规格或纯度
Validated, 1.0 mg/mL
宿主种属
兔(Rabbit)
特异性
CD207
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
A synthetic peptide derived from human CD207 (AA 61-110).
阳性对照
WB: K562, A549, Jurkat, NIH/3T3 and C6 cell lysates.
Langerin Antibody (Ab112769) - Western Blot All lanes: Langerin Antibody (Ab112769) at 1/2000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 37 kDa Observed band size: 37 kDa Exposure time: 5.1 s