Rabbit anti Human Mesp2 Antibody, Polyclonal, could be used for WB and so on.
Application
WB: 1/500-1/1000
Protein Function
Transcription factor with important role in somitogenesis. Defines the rostrocaudal patterning of the somite by participating in distinct Notch pathways. Regulates also the FGF signaling pathway. Specifies the rostral half of the somites. Generates rostro-caudal polarity of somites by down-regulating in the presumptive rostral domain DLL1, a Notch ligand. Participates in the segment border formation by activating in the anterior presomitic mesoderm LFNG, a negative regulator of DLL1-Notch signaling. Acts as a strong suppressor of Notch activity. Together with MESP1 is involved in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm.
规格
产品名称
Mesp2 Antibody
别名
中胚层后部 bHLH 转录因子 2抗体 | Mesp2抗体
英文别名
Basic helix loop helix protein MESP2 antibody | BHLH protein MesP2 antibody | bHLHc6 antibody | Class C basic helix-loop-helix protein 6 antibody | Hypothetical class II basic helix loop helix protein MESP 2 antibody | Hypothetical class II basic helix lo
规格或纯度
ExactAb™, Validated, Carrier Free, 1.0 mg/mL
宿主种属
兔(Rabbit)
特异性
Mesp2
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human MESP2.
Mesp2 Antibody (Ab115041) - Western Blot All lanes: Mesp2 Antibody (Ab115041) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 42 kDa Observed band size: 42, 48 kDa Exposure time: 104.7 s