IME4 | Methyltransferase like protein 3 | Methyltransferase-like protein 3 | Methyltransferase like 3 | METTL3 | MT-A70 | MTA70 | MTA70_HUMAN | N6 adenosine methyltransferase 70 kDa subunit | N6-adenosine-methyltransferase 70 kDa subunit | adoMet-binding
规格或纯度
重组, ExactAb™, 已验证, 见COA
生化机理
N6-methyltransferase that methylates adenosine residues of some mRNAs. N6-methyladenosine (m6A), which is present at internal sites of some mRNAs, may play a role in the efficiency of mRNA splicing, transport or translation.
宿主种属
兔(Rabbit)
特异性
METTL3
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
A synthetic peptide derived from human METTL3 (AA 1-285)
阳性对照
WB: HEK293, Raji, HeLa, Hep G2, RAW 264.7 and C6 cell lysates.
Recombinant METTL3 Antibody (Ab115170) - Western Blot All lanes: Recombinant METTL3 Antibody (Ab115170) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/40000 dilution Predicted band size: 64 kDa Observed band size: 71 kDa Exposure time: 12.1 s
Recombinant METTL3 Antibody (Ab115170) - Western Blot All lanes: Recombinant METTL3 Antibody (Ab115170) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution Predicted band size: 64 kDa Observed band size: 71 kDa Exposure time: 0.3 s
Recombinant METTL3 Antibody (Ab115170) - IP Immunoprecipitate (IP) analysis using the Recombinant METTL3 Antibody (Ab115170) at 1/50 dilution. (WB with Recombinant METTL3 Antibody (Ab115170) at 1/3000 dilution)