Rabbit anti Human Mib1/Mindbomb Antibody, Recombinant, could be used for WB and so on. Application: WB: 1/500-1/2000 Protein Function: E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. Probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis.
Recombinant Mib1/Mindbomb Antibody (Ab115298) - Western Blot All lanes: Recombinant Mib1/Mindbomb Antibody (Ab115298) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/10000 dilution Predicted band size: 110 kDa Observed band size: 114 kDa Exposure time: 13.9 s