Rabbit anti Human NEK2 Antibody, Recombinant, could be used for WB and so on. Application: WB: 1/500-1/1000 Protein Function Protein kinase that is involved in mitotic regulation. Integral component of the mitotic spindle-assembly checkpoint which is necessary for proper chromosome segregation during metaphase-anaphase transition. Required for association of MAD2L1 to kinetochore. Phosphorylates SGOL1. May have a role at the G2-M transition. May also play a role in meiosis. Isoform 1 but not isoform 2 appears to play a role in centrosome splitting. Isoform 1 phosphorylates and activates NEK11 in G1/S-arrested cells. Isoform 2, which is not present in the nucleolus, does not.
规格
产品名称
Recombinant NEK2 Antibody
别名
中心体相关蛋白激酶Nek2抗体 | 重组 NEK2 抗体
英文别名
HSPK 21 antibody | HsPK21 antibody | NEK 2 antibody | NEK2 antibody | NEK2_HUMAN antibody | NEK2A antibody | Never in mitosis A-related kinase 2 antibody | NIMA (never in mitosis gene a) related kinase 2 antibody | NimA like protein kinase 1 antibody | NI
规格或纯度
ExactAb™, Validated, 重组, 1.0 mg/mL
宿主种属
兔(Rabbit)
特异性
NEK2
种属反应性
人(Human)
免疫原
A synthetic peptide derived from human NEK2 (AA 24-37)
Recombinant NEK2 Antibody (Ab117511) - Western Blot All lanes: Recombinant NEK2 Antibody (Ab117511) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution Predicted band size: 52 kDa Observed band size: 47 kDa Exposure time: 57.0 s