Rabbit anti Human NF2/Merlin Antibody, Recombinant, could be used for WB and so on. Application: WB: 1/500-1/1000 Protein Function Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP/DCAF1 E3 ubiquitin-protein ligase complex.
规格
产品名称
Recombinant NF2/Merlin Antibody
别名
2型神经纤维癌重组兔单克隆抗体 | 重组 NF2/Merlin 抗体
英文别名
ACN antibody | BANF antibody | Bilateral acoustic neuroma antibody | MERL_HUMAN antibody | Merlin antibody | Moesin ezrin radixin like protein antibody | Moesin ezrin radizin like antibody | Moesin-ezrin-radixin-like protein antibody | Neurofibromatosis 2
规格或纯度
ExactAb™, Validated, 重组, 1.0 mg/mL
宿主种属
兔(Rabbit)
特异性
NF2 / Merlin
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
A synthetic peptide derived from human NF2/Merlin (AA 582-595).
阳性对照
WB: Mouse brain tissue lysate; HeLa, Hep G2, Jurkat, MCF7, HUVEC, NIH/3T3 and C6 cell lysates.
Recombinant NF2/Merlin Antibody (Ab117821) - Western Blot All lanes: Recombinant NF2/Merlin Antibody (Ab117821) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 70 kDa Observed band size: 72 kDa Exposure time: 13.9 s
ZJ24F0102620
危险品化学品经营许可证（带存储）