Rabbit anti Human PDZK1 Antibody, Recombinant, could be used for WB and so on. Application: WB: 1/500-1/2000 Protein Function A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. May function to connect SCARB1 with the cellular machineries for intracellular cholesterol transport and/or metabolism. May be involved in the regulation of proximal tubular Na(+)-dependent inorganic phosphate cotransport therefore playing an important role in tubule function.
规格
产品名称
Recombinant PDZK1 Antibody
别名
PDZ结构域PDZK1蛋白抗体 | 重组PDZK1抗体
英文别名
CAP70 | CFTR-associated protein of 70 kDa | CLAMP | Na(+)/H(+) exchanger regulatory factor 3 | Na/Pi cotransporter C-terminal-associated protein 1 | NaPi-Cap1 | NHERF3 | NHERF-3 | NHERF3PDZD1Na(+)/H(+) exchange regulatory cofactor NHE-RF3 | PDZ domain con
规格或纯度
重组, ExactAb™, 已验证, 见COA
宿主种属
兔(Rabbit)
特异性
PDZK1
种属反应性
人(Human)
免疫原
A synthesized peptide derived from human PDZK1 ( AA 450-519).
Recombinant PDZK1 Antibody (Ab121120) - Western Blot All lanes: Recombinant PDZK1 Antibody (Ab121120) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 57 kDa Observed band size: 66 kDa Exposure time: 30.0 s