Rabbit anti Human RAB7B Antibody, Recombinant, could be used for WB and so on. Application: WB: 1/1000 Protein Function Controls vesicular trafficking from endosomes to the trans-Golgi network (TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF- and EGFR degradation pathway.
规格
产品名称
Recombinant RAB7B Antibody
别名
RAB7B重组兔单抗 | RAB7B单抗 | RAB7B抗体 | 重组RAB7B抗体
英文别名
MGC16212 | MGC9726 | RAB7 | rab7B | RAB7B, member RAS oncogene family | RAB7B_HUMAN | Ras related protein Rab 7b | Ras-related protein Rab-7B | MGC16212 antibody | MGC9726 antibody | RAB7 antibody | rab7B antibody | RAB7B, member RAS oncogene family antib
规格或纯度
Recombinant, Validated, 1.0 mg/mL
宿主种属
兔(Rabbit)
特异性
RAB7B
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
A synthetic peptide derived from human RAB7B (AA 142-154)
Recombinant RAB7B Antibody (Ab124255) - Western Blot All lanes: Recombinant RAB7B Antibody (Ab124255) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 23 kDa Observed band size: 23 kDa Exposure time: 8.6 s
ZJ24F0607550
危险品化学品经营许可证（带存储）