Rabbit anti Human RALA Antibody, Recombinant, could be used for WB and so on. Application: WB: 1/500-1/1000 Protein Function: Multifuntional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Plays a role in the early stages of cytokinesis and is required to tether the exocyst to the cytokinetic furrow. The RALA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling. Key regulator of LPAR1 signaling and competes with ADRBK1 for binding to LPAR1 thus affecting the signaling properties of the receptor. Required for anchorage-independent proliferation of transformed cells.
MGC48949 antibody | Ral a antibody | Ral A protein antibody | RAL antibody | RALA antibody | RALA_HUMAN antibody | Ras family small GTP binding protein RALA antibody | RAS like protein Aantibody | Ras related protein RalA antibody | Ras-related protein Ra
规格或纯度
ExactAb™, Validated, 重组, 1.0 mg/mL
宿主种属
兔(Rabbit)
特异性
RALA
种属反应性
人(Human)
免疫原
A synthetic peptide derived from human RalA (AA 120-206)
阳性对照
WB: MCF7, Hep G2, HeLa, MOLT-4, HEK293 and HT-29 cell lysates.
Recombinant RALA Antibody (Ab124478) - Western Blot All lanes: Recombinant RALA Antibody (Ab124478) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution Predicted band size: 24 kDa Observed band size: 25 kDa Exposure time: 6.1 s