Rabbit anti Human REST/NRSF Antibody, Recombinant, could be used for WB and so on. Application: WB: 1/500-1/2000 Protein Function: Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier.
Recombinant REST/NRSF Antibody (Ab125080) - Western Blot All lanes: Recombinant REST/NRSF Antibody (Ab125080) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution Predicted band size: 122 kDa Observed band size: 150 kDa Exposure time: 1.0 s