Rabbit anti Human Smad2 Antibody, Recombinant, could be used for WB, IF/ICC and so on.
规格
产品名称
Recombinant Smad2 Antibody
别名
抗Smad2抗体|Smad同源物2重组抗体
英文别名
hMAD-2|hSMAD2|JV18|JV18-1SMAD, mothers against DPP homolog 2 (Drosophila)|MAD homolog 2|Mad protein homolog|Mad, mothers against decapentaplegic homolog 2|MADH2|MADH2MGC34440|MADR2|MADR2MGC22139|Mad-related protein 2|mother against DPP homolog 2|mothers against decapentaplegic homolog 2|Mothers against DPP homolog 2|Sma- and Mad-related protein 2|SMAD 2|SMAD family member 2MAD, mothers against decapentaplegic homolog 2 (Drosophila)|SMAD, mothers against DPP homolog 2|Smad2|Smox|Drosophila, homolog of, MADR2 antibody|hMAD-2 antibody|HsMAD2 antibody|JV18 antibody|JV18-1 antibody|JV181 antibody|MAD antibody|MAD homolog 2 antibody|MAD Related Protein 2 antibody|Mad-related protein 2 antibody|MADH2 antibody|MADR2 antibody|MGC22139 antibody|MGC34440 antibody|Mother against DPP homolog 2 antibody|Mothers against decapentaplegic homolog 2 antibody|Mothers against decapentaplegic, Drosophila, homolog of, 2 antibody|Mothers against DPP homolog 2 antibody|OTTHUMP00000163489 antibody|Sma and Mad related protein 2 antibody|Sma- and Mad-related protein 2 MAD antibody|SMAD 2 antibody|SMAD family member 2 antibody|SMAD, mothers against DPP homolog 2 antibody|SMAD2 antibody
规格或纯度
重组, ExactAb™, 已验证, 见COA
生化机理
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma.
宿主种属
兔(Rabbit)
特异性
SMAD2
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
A synthetic peptide derived from human Smad2 (AA 230-270)
阳性对照
WB: HeLa, Jurkat, Hep G2, MCF7, SH-SY5Y, NIH/3T3 and C6 cell lysates. IF/ICC: HeLa cells.
Recombinant Smad2 Antibody (Ab128194) - Western Blot All lanes: Recombinant Smad2 Antibody (Ab128194) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution Predicted band size: 52 kDa Observed band size: 58 kDa Exposure time: 100.0 s
Recombinant Smad2 Antibody (Ab128194) - IF/ICC Immunofluorescent analysis of HeLa cells, using Recombinant Smad2 Antibody (Ab128194).
应用
应用名称
稀释比例
IF/ICC
1/50 - 1/200
WB
1/1000 - 1/2000
高级数据
关联靶点(人)
SMAD2Tbio母亲反对 decapentaplegic 同源物 2(Mothers against decapentaplegic homolog 2)
(0 活性数据)