Rabbit anti Human TEF1/TEAD-1 Antibody, Recombinant, could be used for WB and so on. Application WB: 1/500-1/1000 Protein Function Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and cooperatively to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription in vivo in a cell-specific manner. The activation function appears to be mediated by a limiting cell-specific transcriptional intermediary factor (TIF). Involved in cardiac development. Binds to the M-CAT motif.
规格
产品名称
Recombinant TEF1/TEAD-1 Antibody
别名
转录增强缔合域蛋白1重组兔单克隆抗体 | 重组 TEF1/TEAD-1 抗体
英文别名
AA antibody | Atrophia areata peripapillary chorioretinal degeneration antibody | NTEF 1 antibody | NTEF-1 antibody | NTEF1 antibody | Protein GT IIC antibody | Protein GT-IIC antibody | REF 1 antibody | REF1 antibody | SV40 transcriptional enhancer facto
规格或纯度
ExactAb™, Validated, 重组, 1.0 mg/mL
宿主种属
兔(Rabbit)
特异性
TEF1/TEAD-1
种属反应性
人(Human),仓鼠(Hamster),大鼠(Rat)
免疫原
A synthetic peptide derived from human TEAD-1 (AA 411-426)
阳性对照
WB: C6, Hep G2, HEK293, A549, MCF7 and HeLa cell lysates.
Recombinant TEF1/TEAD-1 Antibody (Ab130656) - Western Blot All lanes: Recombinant TEF1/TEAD-1 Antibody (Ab130656) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/30000 dilution
Predicted band size: 48 kDa Observed band size: 50 kDa Exposure time: 33.9 s