IIAE6 antibody | MGC35334 antibody | MyD883 antibody | Proline rich vinculin and TIR domain containing protein B antibody | Proline-rich antibody | PRVTIRB antibody | Putative NF kappa B activating protein 502H antibody | Putative NF-kappa-B-activating pr
规格或纯度
重组, ExactAb™, 已验证, 见COA
生化机理
Involved in innate immunity against invading pathogens. Adapter used by TLR3 and TLR4 (through TICAM2) to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively.
Recombinant TRIF Antibody (Ab132451) - Western Blot All lanes: Recombinant TRIF Antibody (Ab132451) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 76 kDa Observed band size: 102 kDa Exposure time: 12.8 s