EST01027 antibody | HHCPA78 antibody | THIF antibody | Thioredoxin binding protein 2 antibody | Thioredoxin interacting protein antibody | Thioredoxin-binding protein 2 antibody | Thioredoxin-interacting protein antibody | TXNIP antibody | TXNIP_HUMAN ant
规格或纯度
重组,ExactAb™,已验证,见COA
生化机理
May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells.
宿主种属
兔(Rabbit)
特异性
TXNIP
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
A synthetic peptide derived from human TXNIP (AA 30-95)
TXNIP Antibody (Ab133095) - Western Blot All lanes: TXNIP Antibody (Ab133095) at 1/500 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 44 kDa Observed band size: 49 kDa Exposure time: 100.0 s
TXNIP Antibody (Ab133095) - Western Blot All lanes: TXNIP Antibody (Ab133095) at 1/500 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 44 kDa Observed band size: 49 kDa Exposure time: 30.0 s
ZJ24F0606813
危险品化学品经营许可证（带存储）