ExactAb™,低内毒素,已验证,无动物源,无叠氮钠,无载体,重组 级 提供 ≥95%(SDS-PAGE&SEC-HPLC) 纯度，适用于对基线干扰要求严格的色谱和分析工作流程。
-80℃储存,避免反复冻融。特低温运输 。请查阅批次 COA 获取详细规格。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
Vopratelimab (anti-ICOS)是一种人源化免疫球蛋白G1-kappa激动剂单克隆抗体，特异性结合到诱导型T细胞CO刺激因子(ICOS)。Vopratelimab (anti-ICOS)保留了物种交叉反应性，对hICOS的亲和力为0.93nM，对大鼠ICOS的亲和力为3.7nM，对mICOS的亲和力为0.64nM。Vopratelimab (anti-ICOS)具有抗肿瘤免疫反应。
Vopratelimab (anti-ICOS) is a humanized immunoglobulin G1-kappa agonist monoclonal antibody that pecifically binds to the Inducible CO-Stimulator of T cells (ICOS). Vopratelimab (anti-ICOS) retains species cross-reactivity with affinities of 0.93 nM to hICOS, 0.46 nM to cynomolgus ICOS, 3.7 nM to rat ICOS, and 0.64 nM to mICOS. Vopratelimab (anti-ICOS) has antitumor immune response.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg
Vopratelimab (anti-ICOS) (Ab176563) - Flow Cytometry
Flow Cytometry analysis of PHA-stimulated (3 days) human peripheral blood lymphocytes labelling ICOS with Vopratelimab (anti-ICOS) (Ab176563) conjugated with biotin (right panel) compared with Human IgG (Ab170213) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156150).
Vopratelimab (anti-ICOS) (Ab176563) - Flow Cytometry
Flow Cytometry analysis of PHA-stimulated (3 days) human peripheral blood lymphocytes labelling ICOS (red) with Vopratelimab (anti-ICOS) (Ab176563) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, human IgG (Ab170213) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.
Vopratelimab (anti-ICOS) (Ab176563) - SEC
The purity of Vopratelimab (anti-ICOS) (Ab176563) is more than 95% verified by HPLC.
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
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通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！
| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
 ZJ24F0911514 |
分析证书 | Ab176563 |
| ZJ24F0911515 |
分析证书 | Ab176563 |
| ZJ24F0911516 |
分析证书 | Ab176563 |
| ZJ23F1001520 |
分析证书 | Ab176563 |
| ZJ23F1001521 |
分析证书 | Ab176563 |
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