ExactAb™,低内毒素,已验证,无动物源,无叠氮钠,无载体,重组 级 提供 ≥95%(SDS-PAGE&SEC-HPLC) 纯度，适用于对基线干扰要求严格的色谱和分析工作流程。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
Alomfilimab (anti-ICOS) 是一种人免疫球蛋白 G1 (IgG1) Kappa 单克隆抗体，可识别诱导型 T 细胞共刺激剂 (ICOS; CD278)，具有潜在的免疫调节和抗肿瘤活性。
Alomfilimab (anti-ICOS) is a human immunoglobulin G1 (IgG1) kappa monoclonal antibody that recognizes inducible T-cell co-stimulator (ICOS; CD278), with potential immunomodulating and antineoplastic activities.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg
Alomfilimab (anti-ICOS) (Ab179101) - Flow Cytometry
Flow Cytometry analysis of 500 ng/mL Ionomycin (I139530) and 10 ng/mL PMA (P408905) co-stimulated Jurkat cells (24h) labelling ICOS (red) with Alomfilimab (anti-ICOS) (Ab179101). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Alomfilimab (anti-ICOS) (Ab179101) - Flow Cytometry
Flow Cytometry analysis of 500 ng/mL Ionomycin (I139530) and 10 ng/mL PMA (P408905) co-stimulated MOLT-4 cells (24h) labelling ICOS (red) with Alomfilimab (anti-ICOS) (Ab179101). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Alomfilimab (anti-ICOS) (Ab179101) - SEC
The purity of Alomfilimab (anti-ICOS) (Ab179101) is more than 95% verified by HPLC.
Alomfilimab (anti-ICOS) (Ab179101) - ELISA
Immobilized Cynomolgus/Rhesus Macaque ICOS/CD278-his a at 2.0 μg/mL can bind Alomfilimab (anti-ICOS) (Ab179101) with the EC₅₀ of 11.35 ng/mL.
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
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| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
 ZJ24F0404227 |
分析证书 | Ab179101 |
| ZJ24F0404228 |
分析证书 | Ab179101 |
| ZJ24F0404229 |
分析证书 | Ab179101 |
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