Olinvacimab (anti-VEGFR2), 血管内皮生长因子受体 2 抑制剂

CAS: 2095504-49-5 货号: Ab182846
有货
级别和纯度: 无动物源 ? 无动物源(Animal Free)—— 不含动物源成分生产,降低污染风险。适用于避免动物源材料的生物制造和培养。 无载体 ? 无载体(Carrier Free)—— 不含添加的载体蛋白/稳定剂。当载体(如 BSA)会干扰偶联或敏感检测时使用。 重组 ? 重组(Recombinant)—— 通过重组表达生产,序列确定、批次稳定。适用于来源明确、无动物源的可重现蛋白。 ExactAb™ ? ExactAb™ —— 阿拉丁强调精准和验证质量的抗体系列。适用于可靠、特异性经验证的抗体应用。 低内毒素 ? 低内毒素级 —— 内毒素降至受控低水平。适用于高内毒素会造成干扰的敏感生物工作。 无叠氮钠 ? 无叠氮(Azide Free)—— 不含叠氮化钠防腐剂。适用于叠氮有毒或有抑制作用的偶联、细胞工作或检测。 已验证 ? 已验证级 —— 发布前在特定应用中确认性能。当需要试剂按声称工作的书面保证时使用。 ≥95%(SDS-PAGE&SEC-HPLC) 见COA
应用
Animal Model, ELISA, Flow Cytometry, Functional Assay
宿主种属
人(Human)
种属反应性
人(Human), 大鼠(Rat), 小鼠(Mouse)
亚型
Human IgG1
偶联
Unconjugated
★
规格
库存
价格
数量
100μg
Ab182846-100μg
现货 Stock Image
¥434.90
1mg
Ab182846-1mg
现货 Stock Image
¥2,144.90
5mg
Ab182846-5mg
现货 Stock Image
¥5,624.90
10mg
Ab182846-10mg
期货 Stock Image
¥11,999.90
请输入您要添加的产品数量

概述

Olinvacimab (anti-VEGFR2) 是一种人抗 VEGFR2 单克隆抗体。Olinvacimab (anti-VEGFR2) 抑制 VEGF 与 KDR 结合,Kd 值为 0.23 nM。Olinvacimab (anti-VEGFR2) 具有抗血管生成活性。Olinvacimab (anti-VEGFR2) 可用于复发性胶质母细胞瘤和乳腺癌的研究。

Olinvacimab (anti-VEGFR2) is a fully human anti-VEGFR2 monoclonal antibody. Olinvacimab (anti-VEGFR2) inhibits VEGF binds to KDR with a Kd value of 0.23 nM. Olinvacimab (anti-VEGFR2) has antiangiogenic activity. Olinvacimab (anti-VEGFR2) can be used for the research of recurrent glioblastoma and breast cancer.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg


规格

产品名称
Olinvacimab (anti-VEGFR2), 血管内皮生长因子受体 2 抑制剂
别名
奥伐西单抗|奥林伐单抗(抗 VEGFR2)
英文别名
CD309 antibody|CD309 antigen antibody|EC 2.7.10.1 antibody|Fetal liver kinase 1 antibody|FLK-1 antibody|FLK1 antibody|FLK1, mouse, homolog of antibody|Kdr antibody|Kinase insert domain receptor (a type III receptor tyrosine kinase) antibody|Kinase insert domain receptor antibody|KRD1 antibody|Ly73 antibody|Protein tyrosine kinase receptor FLK1 antibody|Protein-tyrosine kinase receptor flk-1 antibody|soluble VEGFR2 antibody|Tyrosine kinase growth factor receptor antibody|Vascular endothelial growth factor receptor 2 antibody|VEGFR 2 antibody|VEGFR antibody|VEGFR-2 antibody|VEGFR2 antibody|CD309 antigen|CD309|Fetal liver kinase 1|fetal liver kinase-1|Flk1|Flk-1|FLK1tyrosine kinase growth factor receptor|KDR|kinase insert domain receptor (a type III receptor tyrosine kinase)|Kinase insert domain receptor|KRD1|Ly73|Protein-tyrosine kinase receptor flk-1|soluble VEGFR2|vascular endothelial growth factor receptor 2|VEGF R2|VEGFR|VEGFR2|VEGFR-2
规格或纯度
无载体, 重组, ExactAb™, 低内毒素, 无叠氮钠, 已验证, 无动物源, ≥95%(SDS-PAGE&SEC-HPLC), 见COA
宿主种属
人(Human)
特异性
KDR
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
偶联
Unconjugated
作用类型
抑制剂
作用机制
血管内皮生长因子受体 2 抑制剂
克隆类型
重组抗体
Format
Whole IgG
亚型
Human IgG1
轻链亚型
lambda
纯化方法
Protein A purified
浓度
见COA
CAS编号和信息
2095504-49-5
分子类型
抗体
产品线
生物产品
储存与运输
物理外观
Liquid
储存缓冲液
Supplied as a 0.22μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0
防腐剂
No
储存条件
-80℃储存,避免反复冻融
运输条件
特低温运输
稳定性与储存
在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。
图片

Olinvacimab (anti-VEGFR2) (Ab182846) - Flow Cytometry
Flow Cytometry analysis of HUVEC cells labelling VEGFR2 (red) with Olinvacimab (anti-VEGFR2) (Ab182846). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Olinvacimab (anti-VEGFR2) (Ab182846) - SEC
The purity of Olinvacimab (anti-VEGFR2) (Ab182846) is more than 95% verified by HPLC.

高级数据

关联靶点(人)
KDR Tclin 血管内皮生长因子受体 2(Vascular endothelial growth factor receptor 2) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
KDR Tclin Vascular endothelial growth factor receptor 2 (20924 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
KDR Tclin VEGF-receptor 2 and Fibroblast growth factor receptor 2 (15 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
KDR Tclin VEGF-receptor 2 and Fibroblast growth factor receptor 1 (50 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
KDR Tclin Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2) (14 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
KDR Tclin TEL/KDR (9 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
作用机制
作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献
质检证书(CoA,COO,BSE/TSE 和分析图谱)
C of A & Other Certificates(BSE/TSE, COO):
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找到3个结果

批号(Lot Number) 证书类型 货号
ZJ24F0404829ZJ24F0404829 分析证书 Ab182846
ZJ24F0404830ZJ24F0404830 分析证书 Ab182846
ZJ24F0404831ZJ24F0404831 分析证书 Ab182846
技术文档和文章
溶液计算器

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